Biology of Extracellular Matrix

Extracellular Matrix Omics

Editors: Ricard-Blum, Sylvie (Ed.)

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  • Provides a state-of-the art overview of extracellular matrix omics
  • Focuses especially on glycomics and glycobioinformatics
  • Elaborates on guiding principles for scientific data management
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eBook 117,69 €
price for Spain (gross)
  • ISBN 978-3-030-58330-9
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Hardcover 145,59 €
price for Spain (gross)
  • ISBN 978-3-030-58329-3
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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About this book

This book covers different omics aspects related to the extracellular matrix (ECM), namely specific omics resources focused on the extracellular matrix (e.g., databases, repositories and atlases), quantitative proteomics applied to specific extracellular matrices (e.g. basement membranes), biological processes such as ECM degradation (degradomics), cell-matrix interactions (adhesomes), signaling pathways, biomarker discovery and diseases, and interactomics (extracellular matrix interaction networks including not only protein-protein but also protein-glycosaminoglycan interactions). The volume also includes recent advances in glycomics and glycobioinformatics applied to proteoglycans and glycosaminoglycans, which are key biological players. The use of omics data to build dynamic models of ECM-regulated biological pathways is addressed, together with the requirement to standardize omic data, which is a prerequisite for the FAIR (Findability, Accessibility, Interoperability, and Reusability) guiding principles for scientific data management.

This book will be of great interest to a broad readership from beginners to advanced researchers, who are interested in extracellular matrix omics and will inspire future research topics.

 

About the authors

Sylvie Ricard-Blum is Professor of Biochemistry at the University of Lyon (France). She studies the structure, interactions and functions of the extracellular matrix (ECM) using biochemistry, biophysics, bioinformatics and systems biology. Her laboratory has developed a roadmap and tools to build and contextualize ECM interaction networks, including the database MatrixDB. She has identified several hundreds of ECM interactions, and built interaction networks of ECM proteins, bioactive ECM fragments (matricryptins), glycosaminoglycans and proteoglycans leading to the prediction of new functions for a number of them. Her current research aims at determining the role of intrinsic disorder, cross-linking, proteolysis and mutations in rewiring ECM networks in disease with a focus on matricryptins, lysyl oxidases and syndecans. She has been Secretary and President of the French Society for Matrix Biology, and serves as Associate Editor of Matrix Biology and Matrix Biology Plus, Editor of the newsletter of the International Society for Matrix Biology, and as President of the International Society for Matrix Biology (2019-2020).

Table of contents (10 chapters)

Table of contents (10 chapters)

Buy this book

eBook 117,69 €
price for Spain (gross)
  • ISBN 978-3-030-58330-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 145,59 €
price for Spain (gross)
  • ISBN 978-3-030-58329-3
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Extracellular Matrix Omics
Editors
  • Sylvie Ricard-Blum
Series Title
Biology of Extracellular Matrix
Series Volume
7
Copyright
2020
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-58330-9
DOI
10.1007/978-3-030-58330-9
Hardcover ISBN
978-3-030-58329-3
Series ISSN
0887-3224
Edition Number
1
Number of Pages
VIII, 225
Number of Illustrations
2 b/w illustrations, 20 illustrations in colour
Topics