Editors:
- An overview of the role that the 5-HT2B receptor plays in human physiology
- Covers molecular and physiological aspects
- Serves as a good reference for biological scientists and medical doctors
Part of the book series: The Receptors (REC, volume 35)
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Table of contents (22 chapters)
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Front Matter
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Development and Growth
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Front Matter
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Peripheral Actions
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Front Matter
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Brain Actions
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Front Matter
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About this book
Editors and Affiliations
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Inserm, U1270, Institut du Fer a Moulin, Paris, France
Luc Maroteaux
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Pharmacology, Strasbourg Medical school, Strasbourg, France
Laurent Monassier
About the editors
Laurent Monassier is Professor of Pharmacology at the Strasbourg's University, Strasbourg, France, where he leads the Laboratory of NeuroCardiovascular Pharmacology and Toxicology (UR 7296). His research group is interested in the pharmacological modulation of the autonomic nervous system in cardiovascular diseases. In particular, he is interested in developing 5-HT2 receptor antagonists to protect cardiac valves lesions and other 5-HT ligands in various diseases affecting the lung, the heart and the central nervous system. He is also developing new compounds dedicated to various metabolic disorders associated with the metabolic syndrome.
Luc Maroteaux is Research Director at INSERM U1270, Institut du Fer à Moulin, Sorbonne University, Paris, France, and is leading the "Serotonin, microglia, plasticity and pathologies" team. His research is focusing into the control of neuronal plasticity in the central nervous system and its pathological and pharmacological alterations. In particular, the team discovered that the serotonin 5-HT2B receptor acts in the brain by increasing extracellular serotonin concentrations by a neuron control mechanism that produces serotonin, and that this receptor is involved in impulsive and depressive behaviors. They are currently working on an original concept focusing on the inflammatory origin of certain psychiatric illnesses, always focusing on serotonin.
​Bibliographic Information
Book Title: 5-HT2B Receptors
Book Subtitle: From Molecular Biology to Clinical Applications
Editors: Luc Maroteaux, Laurent Monassier
Series Title: The Receptors
DOI: https://doi.org/10.1007/978-3-030-55920-5
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021
Hardcover ISBN: 978-3-030-55919-9Published: 13 March 2021
Softcover ISBN: 978-3-030-55922-9Published: 14 March 2022
eBook ISBN: 978-3-030-55920-5Published: 12 March 2021
Series ISSN: 1048-6909
Series E-ISSN: 2524-6488
Edition Number: 1
Number of Pages: VIII, 401
Number of Illustrations: 44 b/w illustrations
Topics: Neurosciences, Human Physiology