Overview
- Highlights the importance of antigen presentation in peripheral tissues
- Updates the latest mechanism for forming inducible lymphoid organs (ILOs)
- Provides a unique perspective on ILOs in different tissues, in different conditions
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 426)
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Table of contents (7 chapters)
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Front Matter
Keywords
About this book
This book sheds new light on “inducible” lymphoid organs (ILOs): antigen presentation sites that are generated de novo in peripheral tissues under various pathogenic conditions. Accomplished immunologists demonstrate that the physiological role of these ILOs is completely different from that of central lymphoid organs, i.e., the lymph nodes or spleen. In addition to the central organs, the ILOs are considered essential structures for the efficient elicitation of adaptive immune responses in lesions.
The respective chapters highlight examples from multiple sites, e.g. the skin, lung, intestinal tract, genital tract, the synovial membrane of the joints and artificial lymph nodes. Accordingly, readers will learn that ILO structure and function can vary substantially, depending on the context.
Presenting the results of the latest immunological research, the book offers a fascinating and insightful read for both scientists and clinicians in the areas of infectious and immune-associated diseases.
Editors and Affiliations
About the editors
Dr. Gyohei Egawa graduated from Saga Medical school (Saga, Japan) in 2001 and was trained in the department of dermatology in Kyoto University (Kyoto, Japan). After getting his PhD, he worked at Kyoto University hospital and Centenary Institute (Sydney, Australia). Currently, he is a senior lecturer at the department of Dermatology in Kyoto University. His main interests are the barrier function of the skin and intravital visualization of the skin immunity.
Bibliographic Information
Book Title: Inducible Lymphoid Organs
Editors: Kenji Kabashima, Gyohei Egawa
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-030-51747-2
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-51746-5Published: 18 August 2020
Softcover ISBN: 978-3-030-51749-6Published: 18 August 2021
eBook ISBN: 978-3-030-51747-2Published: 17 August 2020
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: VII, 160
Number of Illustrations: 1 b/w illustrations
Topics: Immunology, Infectious Diseases, Cancer Research, Human Physiology