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Tumor Microenvironments in Organs

From the Brain to the Skin – Part A

  • Provides a comprehensive overview of the state-of-the-art research on the tumor microenvironment in over thirty human organs, including the thyroid, bladder, intestine, tongue, and more
  • Illustrates how cancer cells in different human tissues are affected by different components of the tumor microenvironment
  • Identifies specific components in the tumor microenvironment for each tissue type that may become specific targets for cancer treatment

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1226)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xii
  2. The Intestinal Tumour Microenvironment

    • J. K. H. Leman, L. Munoz-Erazo, R. A. Kemp
    Pages 1-22
  3. Gastric Tumor Microenvironment

    • Armando Rojas, Paulina Araya, Ileana Gonzalez, Erik Morales
    Pages 23-35
  4. Parathyroid Tumor Microenvironment

    • Chiara Verdelli, Valentina Vaira, Sabrina Corbetta
    Pages 37-50
  5. Microenvironment in Cardiac Tumor Development: What Lies Beyond the Event Horizon?

    • Konstantinos S. Mylonas, Ioannis A. Ziogas, Dimitrios V. Avgerinos
    Pages 51-56
  6. Adipose Tumor Microenvironment

    • Abbie Zewdu, Lucia Casadei, Raphael E. Pollock, Danielle Braggio
    Pages 73-86
  7. Appendix Tumor Microenvironment

    • Luca Roncati, Paolo Gasparri, Graziana Gallo, Giuditta Bernardelli, Giuliana Zanelli, Antonio Manenti
    Pages 87-95
  8. Spinal Cord Tumor Microenvironment

    • Laurèl Rauschenbach
    Pages 97-109
  9. Cancer Stem Cell Niche and Immune-Active Tumor Microenvironment in Testicular Germ Cell Tumors

    • Katarina Kalavska, Lucia Kucerova, Silvia Schmidtova, Michal Chovanec, Michal Mego
    Pages 111-121
  10. Tumour Microenvironment in Skin Carcinogenesis

    • Simona Roxana Georgescu, Mircea Tampa, Cristina Iulia Mitran, Madalina Irina Mitran, Constantin Caruntu, Ana Caruntu et al.
    Pages 123-142
  11. Back Matter

    Pages 143-147

About this book

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in over thirty human organs, including the parathyroid gland, heart, intestine, testicles, and more.


Taken alongside its companion volumes, these books update us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. Tumor Microenvironments in Organs: From the Brain to the Skin – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Editors and Affiliations

  • Columbia University Medical Center, Department of Radiology, New York, NY, USA, Federal University of Minas Gerais, Department of Pathology, Belo Horizonte, Brazil

    Alexander Birbrair

About the editor

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Bibliographic Information

  • Book Title: Tumor Microenvironments in Organs

  • Book Subtitle: From the Brain to the Skin – Part A

  • Editors: Alexander Birbrair

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-36214-0

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-36213-3Published: 07 February 2020

  • Softcover ISBN: 978-3-030-36216-4Published: 07 February 2021

  • eBook ISBN: 978-3-030-36214-0Published: 06 February 2020

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XII, 147

  • Number of Illustrations: 1 b/w illustrations, 24 illustrations in colour

  • Topics: Cell Biology, Cancer Research, Oncology

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access