Editors:
The book highlights the relevance of human physiology and disease susceptibility
Can be read by both general and specialized readers
Studies acquired epigenetic inheritance of phenotypic setpoints
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Table of contents (12 chapters)
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Front Matter
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The Physiology of Gene/Environment Interaction
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Front Matter
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Gene-Environment Interaction and Disease Susceptibility
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Front Matter
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Genome/Epigenome
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Front Matter
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Back Matter
About this book
The genotype/phenotype dichotomy is being slowly replaced by a more complex relationship whereby the majority of phenotypes arise from interactions between one’s genotype and the environment in which one lives. Interestingly, it seems that not only our lives, but also our ancestors’ lives, determine how we look.
This newly recognized form of inheritance is known as (epi)genetic, as it involves an additional layer of information on top of the one encoded by the genes. Its discovery has constituted one of the biggest paradigm shifts in biology in recent years. Understanding epigenetic factors may help explain the pathogenesis of several complex human diseases (such as diabetes, obesity and cancer) and provide alternative paths for disease prevention, management and therapy.
This book introduces the reader to the importance of the environment for our own health and the health of our descendants, sheds light on the current knowledge on epigenetic inheritance and opens a window to future developments in the field.
Editors and Affiliations
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Head of the Environmental Epigenetics Group, Institute of Experimental Genetics & German Center for Diabetes Research (DZD), Helmholtz Zentrum München GmbH – German Research Center for Environmental Health, Neuherberg, Germany
Raffaele Teperino
About the editor
Bibliographic Information
Book Title: Beyond Our Genes
Book Subtitle: Pathophysiology of Gene and Environment Interaction and Epigenetic Inheritance
Editors: Raffaele Teperino
DOI: https://doi.org/10.1007/978-3-030-35213-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-35212-7Published: 25 January 2020
Softcover ISBN: 978-3-030-35215-8Published: 25 January 2021
eBook ISBN: 978-3-030-35213-4Published: 24 January 2020
Edition Number: 1
Number of Pages: VIII, 266
Number of Illustrations: 1 b/w illustrations, 10 illustrations in colour
Topics: Human Genetics, Genetics and Genomics, Genetic Engineering