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  • © 2020

Precision in Pulmonary, Critical Care, and Sleep Medicine

A Clinical and Research Guide

  • Provides the first resource for in depth coverage of the use of precision medicine in pulmonary, critical care and sleep medicine
  • Detail the use of genetics, diagnostics and biomarkers, phenotyping, mobile health, and telemedicine in precision medicine
  • Written by leaders in the fields of pulmonary, critical care and sleep medicine

Part of the book series: Respiratory Medicine (RM)

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xv
  2. Introduction

    1. Front Matter

      Pages 1-1
    2. Introduction

      • Jose L. Gomez, Naftali Kaminski, Blanca E. Himes
      Pages 3-8
  3. Genetics

    1. Front Matter

      Pages 9-9
    2. Genetics and Pharmacogenetics of Asthma

      • Mengyuan Kan, Blanca E. Himes
      Pages 25-37
    3. Genetics and Pharmacogenetics of COPD

      • Yohan Bossé, Michael H. Cho
      Pages 39-55
    4. The Evolution of Precision Medicine in Cystic Fibrosis

      • Yukiko Kunitomo, Clemente J. Britto
      Pages 57-69
    5. Genetics of Idiopathic Pulmonary Fibrosis

      • Susan K. Mathai, David A. Schwartz
      Pages 71-85
    6. Genetics of Lung Cancer

      • Katrina Steiling, Joshua D. Campbell
      Pages 87-103
  4. Biomarkers

    1. Front Matter

      Pages 105-105
    2. Chest Imaging for Precision Medicine

      • Samuel Y. Ash, Raúl San José Estépar, George R. Washko
      Pages 107-115
    3. Biobanking for Pulmonary, Critical Care, and Sleep Medicine

      • Julia Winkler, Erica L. Herzog
      Pages 117-130
    4. Biomarkers in Obstructive Airway Diseases

      • Rachel S. Kelly, Kathleen A. Stringer, Chris H. Wendt
      Pages 131-153
    5. Biomarkers in Interstitial Lung Diseases

      • Isis E. Fernandez, Oliver Eickelberg
      Pages 155-165
    6. Molecular Diagnostics in Pulmonary Infections

      • Catherine A. Gao, John C. Huston, Patricia Valda Toro, Samir Gautam, Charles S. Dela Cruz
      Pages 167-184
    7. Biomarkers in Critical Care Illness: ARDS and Sepsis

      • Simon P. F. Lambden, Charlotte Summers
      Pages 185-198
  5. Precise Phenotyping

    1. Front Matter

      Pages 199-199
    2. Lessons for Precision Medicine from Lung Cancer

      • Brett C. Bade, Finbar T. Foley, Lynn T. Tanoue
      Pages 201-223
    3. COPD Phenotyping

      • Emmet O’Brien, Frank C. Sciurba, Jessica Bon
      Pages 225-239

About this book

This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine. It combines fundamental concepts of the field with state-of-the-art studies and how they translate into individual preventive, diagnostic and therapeutic plans.

 

Precision medicine is focused on the integration of individual variability with disease prevention and treatment principles derived from population studies. This concept has risen to prominence in recent years in parallel with advances in genetics, molecular diagnostics and novel target-specific therapies. This fundamental shift in the approach to treatment has broad implications in how we prevent, diagnose and treat disease. Describing key concepts of precision medicine and relating these to pulmonary, critical care and sleep disorders is essential to educate relevant stakeholders and increase the impact of pulmonary precision medicine.

                 

The book is organized into seven sections: introduction; genetics; biomarkers; precise phenotyping; mobile health, wearables and telemedicine; precision therapeutics; and enabling widespread adoption of precision medicine. The chapters are organized with an introduction to the specific theme, followed by its basic concepts. They then delve into how these basic concepts relate to the larger theme of precision medicine, new precision medicine approaches to dealing with these problems, and key takeaway points. Liberally illustrated with images, figures, and tables, the text is thorough and intuitive for clinicians and researchers to learn the processes and applications of precision medicine.

 

This is an ideal guide for clinicians to learn new precision medicine concepts in the fields of genetics, genomics, mobilehealth, and how they apply to their practice and their patients, as well as researchers seeking a basic understanding of precision medicine to assist in designing future research studies. 

Editors and Affiliations

  • Assistant Professor Pulmonary, Critical Care and Sleep Medicine Section, Department of Medicine, Yale University School of Medicine, New Haven, USA

    Jose L. Gomez

  • Assistant Professor of Informatics, Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, USA

    Blanca E. Himes

  • Boehringer-Ingelheim Endowed, Professor of Internal Medicine, Chief of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, USA

    Naftali Kaminski

About the editors

Jose L. Gomez, MD, MS, ATSF

Assistant Professor

Pulmonary, Critical Care and Sleep Medicine Section

Department of Medicine

Yale University School of Medicine

New Haven, CT, USA


Blanca E. Himes, PhD

Assistant Professor of Informatics

Department of Biostatistics, Epidemiology and Informatics

University of Pennsylvania

Philadelphia, PA, USA


Naftali Kaminski, MD, FERS, ATSF

Boehringer-Ingelheim Endowed Professor of Internal Medicine

Chief of Pulmonary, Critical Care and Sleep Medicine

Department of Medicine

Yale University School of Medicine

New Haven, CT, USA

Bibliographic Information

  • Book Title: Precision in Pulmonary, Critical Care, and Sleep Medicine

  • Book Subtitle: A Clinical and Research Guide

  • Editors: Jose L. Gomez, Blanca E. Himes, Naftali Kaminski

  • Series Title: Respiratory Medicine

  • DOI: https://doi.org/10.1007/978-3-030-31507-8

  • Publisher: Humana Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-31506-1Published: 31 January 2020

  • Softcover ISBN: 978-3-030-31509-2Published: 26 August 2021

  • eBook ISBN: 978-3-030-31507-8Published: 30 January 2020

  • Series ISSN: 2197-7372

  • Series E-ISSN: 2197-7380

  • Edition Number: 1

  • Number of Pages: XV, 441

  • Number of Illustrations: 8 b/w illustrations, 63 illustrations in colour

  • Topics: Pneumology/Respiratory System, Intensive / Critical Care Medicine

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access