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Advances in Experimental Medicine and Biology

The Biology of mRNA: Structure and Function

Editors: Oeffinger, Marlene, Zenklusen, Daniel (Eds.)

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  • mRNA centric view on gene regulation depicts the most recent findings in mRNA biology in a comprehensive mannerfeatures new aspects of mRNA disease relations and mRNA structure

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eBook 128,39 €
price for Spain (gross)
  • ISBN 978-3-030-31434-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 166,39 €
price for Spain (gross)
Softcover 124,79 €
price for Spain (gross)
About this book

The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting on the mRNAs, leading to a properly folded complex. This book shows how new technologies have led to a better understanding of these processes and their connected diseases.The book is written for scientists in fundamental and applied biomedical research working on different aspects of gene regulation. It is also targeted to an audience that is not implicated in these fields directly, but wants to gain a better understanding of mRNA biology.

About the authors

Marlene Oeffinger is Associate Research Professor at the Institut de recherches cliniques de Montréal (IRCM) and the Department of biochemistry and molecular medicine at the Université de Montréal in Montréal, Canada, and Adjunct Professor in the Division of Experimental Medicine at McGill University. Her laboratory uses Proteomic, RNomic and biochemical approaches to study the regulation, dynamics and functional niches of RNA maturation pathways and their implications in neurodegenerative diseases.

Daniel Zenklusen is an Associate Professor at the Department of biochemistry and molecular medicine at the Université de Montréal in Montréal, Canada. His laboratory uses single molecule and super-resolution microscopy approaches to study different aspects of gene expression in single cells, including RNA transport and localization, lncRNAs function and mRNP organization.

Table of contents (10 chapters)

Table of contents (10 chapters)
  • Mechanism and Regulation of Co-transcriptional mRNP Assembly and Nuclear mRNA Export

    Pages 1-31

    Wende, Wolfgang (et al.)

  • It’s Not the Destination, It’s the Journey: Heterogeneity in mRNA Export Mechanisms

    Pages 33-81

    Scott, Daniel D. (et al.)

  • View from an mRNP: The Roles of SR Proteins in Assembly, Maturation and Turnover

    Pages 83-112

    Wegener, Marius (et al.)

  • The Nuclear RNA Exosome and Its Cofactors

    Pages 113-132

    Schmid, Manfred (et al.)

  • 3′-UTRs and the Control of Protein Expression in Space and Time

    Pages 133-148

    Beilharz, Traude H. (et al.)

Buy this book

eBook 128,39 €
price for Spain (gross)
  • ISBN 978-3-030-31434-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 166,39 €
price for Spain (gross)
Softcover 124,79 €
price for Spain (gross)
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Bibliographic Information

Bibliographic Information
Book Title
The Biology of mRNA: Structure and Function
Editors
  • Marlene Oeffinger
  • Daniel Zenklusen
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1203
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-31434-7
DOI
10.1007/978-3-030-31434-7
Hardcover ISBN
978-3-030-31433-0
Softcover ISBN
978-3-030-31436-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 312
Number of Illustrations
1 b/w illustrations, 29 illustrations in colour
Topics