Get 40% off of select print and eBooks in Engineering & Materials Science!

Structure and Bonding

Metallocofactors that Activate Small Molecules

With Focus on Bioinorganic Chemistry

Editors: Ribbe, Markus W. (Ed.)

Free Preview
  • Presents an overview of the fundamental chemistry of metallocofactors within the field of bioinorganic chemistry
  • Provides a review of the mechanistic understanding of metallocofactors
  • Multi-authored volume with contributions from world renowned experts in the field
see more benefits

Buy this book

eBook 130,89 €
price for Spain (gross)
  • ISBN 978-3-030-25897-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 228,79 €
price for Spain (gross)
  • ISBN 978-3-030-25896-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

This volume highlights recent progress on the fundamental chemistry and mechanistic understanding of metallocofactors, with an emphasis on the major development in these areas from the perspective of bioinorganic chemistry. 
Metallocofactors are essential for all forms of life and include a variety of metals, such as iron, molybdenum, vanadium, and nickel. Structurally fascinating metallocofactors featuring these metals are present in many bacteria and mediate remarkable metabolic redox chemistry with small molecule substrates, including N2, CO, H2, and CO2. Current interest in understanding how these metallocofactors function at the atomic level is enormous, especially in the context of sustainably feeding and fueling our planet; if we can understand how these cofactors work, then there is the possibility to design synthetic catalysts that function similarly. 

About the authors

The focus of Dr. Ribbe’s research is the assembly and mechanism of nitrogenase, one of the most complex metalloenzymes known to date. Nitrogenase can be appreciated from the perspective of the useful agricultural and industrial products it generates, namely, ammonia, hydrogen and hydrocarbons. Since the beginning of his independent career, Dr. Ribbe has focused his efforts on investigating the biosynthesis of the Mo-nitrogenase from Azotobacter vinelandii and, in particular, the unique metal centers of its MoFe protein component: FeMoco and P-cluster. Results of these studies have firmly established nitrogenase MoFe protein as a model system that could be used to deduce the general mechanism of metal cluster assembly and develop successful strategies for synthesizing bio-inspired catalysts for industrial usage. Recently, Dr. Ribbe expanded his research to the investigation of the structure and function of the “alternative” V-nitrogenase from Azotobacter vinelandii. His discovery that V-nitrogenase can convert CO to hydrocarbons provides a potential blueprint for developing cost-efficient processes for industrial production of biofuels in the future.

Table of contents (6 chapters)

Table of contents (6 chapters)
  • Looking at Nitrogenase: Insights from Modern Structural Approaches

    Pages 1-13

    Wenke, Belinda B. (et al.)

  • Current Understanding of the Biosynthesis of the Unique Nitrogenase Cofactor Core

    Pages 15-31

    Hiller, Caleb J. (et al.)

  • Recent Advances in the Chemical Synthesis of Nitrogenase Model Clusters

    Pages 33-61

    Tanifuji, Kazuki (et al.)

  • The Catalytic Mechanisms of the Molybdenum and Tungsten Enzymes

    Pages 63-100

    Crawford, Andrew M. (et al.)

  • The Role of the Pyranopterin Dithiolene Component of Moco in Molybdoenzyme Catalysis

    Pages 101-151

    Nieter Burgmayer, Sharon J. (et al.)

Buy this book

eBook 130,89 €
price for Spain (gross)
  • ISBN 978-3-030-25897-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 228,79 €
price for Spain (gross)
  • ISBN 978-3-030-25896-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Metallocofactors that Activate Small Molecules
Book Subtitle
With Focus on Bioinorganic Chemistry
Editors
  • Markus W. Ribbe
Series Title
Structure and Bonding
Series Volume
179
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-25897-9
DOI
10.1007/978-3-030-25897-9
Hardcover ISBN
978-3-030-25896-2
Series ISSN
0081-5993
Edition Number
1
Number of Pages
VII, 169
Number of Illustrations
9 b/w illustrations, 61 illustrations in colour
Topics