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Osteosarcopenia: Bone, Muscle and Fat Interactions

Editors: Duque, Gustavo (Ed.)

  • Presenting evidence from bench to bedside
  • Divided into clear parts
  • Written by leaders in the field
  • Foreword by Professor Cyrus Cooper
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Buy this book

eBook 101,14 €
price for Spain (gross)
  • The eBook version of this title will be available soon
  • Due: December 21, 2019
  • ISBN 978-3-030-25890-0
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
Hardcover 166,39 €
price for Spain (gross)
  • Due: December 21, 2019
  • ISBN 978-3-030-25889-4
  • Free shipping for individuals worldwide
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies.

With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide.

Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat –  followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons.

This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population.
The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.



About the authors

Professor Gustavo Duque is a world leader in ageing and musculoskeletal research. Prof. Duque is a geriatrician and a clinical and biomedical researcher with special interest in the mechanisms and treatment of osteoporosis, sarcopenia and frailty in older persons.

Buy this book

eBook 101,14 €
price for Spain (gross)
  • The eBook version of this title will be available soon
  • Due: December 21, 2019
  • ISBN 978-3-030-25890-0
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
Hardcover 166,39 €
price for Spain (gross)
  • Due: December 21, 2019
  • ISBN 978-3-030-25889-4
  • Free shipping for individuals worldwide
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Osteosarcopenia: Bone, Muscle and Fat Interactions
Editors
  • Gustavo Duque
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-25890-0
DOI
10.1007/978-3-030-25890-0
Hardcover ISBN
978-3-030-25889-4
Edition Number
1
Number of Pages
XVI, 383
Number of Illustrations
14 b/w illustrations, 28 illustrations in colour
Topics