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The Mast Cell

A Multifunctional Effector Cell

Authors: Ribatti, Domenico

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  • This book contains a comprehensive and updated view of Mast Cell Biology
  • Broadens the understanding of Mast Cells from their classic immunological role to include their role in human health homeostasis, disease response and tissue regeneration
  • This highly informative book is particularly relevant to students and academics interested in cancer, neurodegeneration, angiogenesis, inflammation and related fields
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eBook 83,29 €
price for Spain (gross)
  • Due: September 1, 2019
  • ISBN 978-3-030-24190-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
Hardcover 135,19 €
price for Spain (gross)
  • ISBN 978-3-030-24189-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

Mast cells (MC) are phylogenetically old cells which are distributed throughout the human organism. MC are found in almost all of the major organs and tissues of the body, particularly in association with connective tissue structures such as blood vessels, lymphatic vessels and nerves, and in proximity to surfaces that interface the external environment, such as those of the respiratory and gastrointestinal system and the skin. This selective accumulation at tissue sites where foreign material attempts to invade the host suggests that MC are among the first cells to initiate defensive mechanisms. MC have long been recognized as key cells of type I hypersensitivity reactions. Several lines of evidence, however, indicate that they not only express critical effector functions in classic IgE-associated allergic disorders, but also play important roles in host defense against parasites, bacteria and perhaps even viruses. Indeed, it is now clear that MC can contribute to host defense in the context of either acquired or innate immune responses through the release of a myriad of pro-inflammatory and immunoregulatory molecules and the expression of a wide spectrum of surface receptors for cytokines and chemokines. Moreover, there is growing evidence that MC exert distinct non-immunological functions, playing a relevant role in tissue homeostasis, remodeling and fibrosis as well as in the processes of tissue angiogenesis.

About the authors


The author, Domenico Ribatti, Full professor of the University of Bari, is an expert in the field of Mast Cells with more than 800 publications.

Table of contents (12 chapters)

Table of contents (12 chapters)

Buy this book

eBook 83,29 €
price for Spain (gross)
  • Due: September 1, 2019
  • ISBN 978-3-030-24190-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
Hardcover 135,19 €
price for Spain (gross)
  • ISBN 978-3-030-24189-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
The Mast Cell
Book Subtitle
A Multifunctional Effector Cell
Authors
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-24190-2
DOI
10.1007/978-3-030-24190-2
Hardcover ISBN
978-3-030-24189-6
Edition Number
1
Number of Pages
VII, 112
Number of Illustrations
4 b/w illustrations, 8 illustrations in colour
Topics