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Pot, Atom, and Step Economy (PASE) Synthesis

  • Book
  • © 2019

Overview

Authors:
  1. Wei Zhang

    1. Chemistry Department, University of Massachusetts Boston, Boston, USA

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    You can also search for this author in PubMed   Google Scholar

  2. Wen-Bin Yi

    1. School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, China

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • Includes reaction mechanisms
  • Exclusively features multicomponent reactions
  • Focuses on the green chemistry aspects of multicomponent reactions

Part of the book series: SpringerBriefs in Molecular Science (BRIEFSMOLECULAR)

Part of the book sub series: SpringerBriefs in Green Chemistry for Sustainability (GREENCHEMIST)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. Introduction to PASE Synthesis

    • Wei Zhang, Wen-Bin Yi
    Pages 1-4

  3. One-Pot Reactions

    • Wei Zhang, Wen-Bin Yi
    Pages 5-13

  4. Cascade Reactions

    • Wei Zhang, Wen-Bin Yi
    Pages 15-26

  5. Multicomponent Reactions (MCRs)

    • Wei Zhang, Wen-Bin Yi
    Pages 27-40

  6. Applications of PASE Synthesis

    • Wei Zhang, Wen-Bin Yi
    Pages 41-47

  7. Conclusive Remarks

    • Wei Zhang, Wen-Bin Yi
    Pages 49-49
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Keywords

About this book

This book emphasizes the atom economy aspect of multicomponent reactions. It describes how this methodology has been applied to several named reactions. Among the “twelve principles of green chemistry”, atom economy addresses ‘synthetic efficiency’. A multicomponent reaction can be defined as an energy, cost, and time efficient method for organic synthesis. Instead of making one or two bonds in a chemical transformation, multicomponent reactions generate several chemical bonds in a single operation. This book presents a series of detailed reaction mechanisms that beautifully illustrate this principle. Multicomponent reactions are widely applied to the preparation of complex and diverse molecular structures in academic and industrial research laboratories. As such, this book is targeted at researchers involved in green organic chemistry.

Authors and Affiliations

  • Chemistry Department, University of Massachusetts Boston, Boston, USA

    Wei Zhang

  • School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, China

    Wen-Bin Yi

About the authors

Wei Zhang, Ph.D.
Associate Professor
Department of Chemistry
University of Massachusetts Boston
HIGHLIGHTS
Research areas: fluorous technology, medicinal chemistry, chemical library synthesis, free radical chemistry, and green chemistry
The 3rd most published author in fluorous chemistry (after D. P. Curran and J. A. Gladysz)
Over 140 publications including 3 Chemical Reviews and 3 Tetrahedron Reports articles
Over 2,900 citations (H-Index 30), the top 1% of the cited authors for journals in the Life Sciences.

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