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Evolutionary Concepts in Immunology

  • Textbook
  • © 2019

Overview

Authors:
  1. Robert Jack

    1. Department of Immunology, University of Greifswald, Greifswald, Germany

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  2. Louis Du Pasquier

    1. Department of Environmental Sciences, Zoology, University of Basel, Basel Stadt, Switzerland

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  • Supplements existing textbooks on immunology by providing an evolutionary perspective on the subject

  • Unifies and explains the diversity of the immune system by placing it in its evolutionary context

  • Helps students to fit their own area of interest into context with this complex field

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-xvi
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  2. What Makes Evolution Tick?

    • Robert Jack, Louis Du Pasquier
    Pages 1-16

  3. From Unicellular to Metazoan Immunity

    • Robert Jack, Louis Du Pasquier
    Pages 17-32

  4. Innate Immunity

    • Robert Jack, Louis Du Pasquier
    Pages 33-69

  5. The Triumph of Individualism: Evolution of Somatically Generated Adaptive Immune Systems

    • Robert Jack, Louis Du Pasquier
    Pages 71-117

  6. The Other Side of the Arms Race

    • Robert Jack, Louis Du Pasquier
    Pages 119-130

  7. Postface

    • Robert Jack, Louis Du Pasquier
    Pages 131-132

  8. Back Matter

    Pages 133-145
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Keywords

About this book

Immunology is a nodal subject that links many areas of biology. It permeates the biosciences, and also plays crucial roles in diagnosis and therapy in areas of clinical medicine ranging from the control of infectious and autoimmune diseases to tumour therapy. Monoclonal antibodies and small molecule modulators of immunity are major factors in the pharmaceutical industry and now constitute a multi billion dollar business. Students in these diverse areas are frequently daunted by the complexity of immunology and the astonishing array of unusual mechanisms that go to make it up.

Starting from Dobzhansky’s famous slogan, “Nothing in biology makes sense except in the light of evolution”, this book will serve to illuminate how evolutionary forces shaped immunity and thus provide an explanation for how many of its counter intuitive oddities arose. By doing so it will provide a conceptual framework on which students may organise the rapidly growing flood of immunological knowledge.


Authors and Affiliations

  • Department of Immunology, University of Greifswald, Greifswald, Germany

    Robert Jack

  • Department of Environmental Sciences, Zoology, University of Basel, Basel Stadt, Switzerland

    Louis Du Pasquier

About the authors

Prof. Jack has been trained as an immunologist in Prof Klaus Rajewsky´s lab in Cologne, and worked in developmental biology at Prof. Walter Gehring´s lab in Basel; subsequently, he has been Professor for Immunology for many years at the University of Greifswald. For more than 10 years, he has been active in the organizing committee of the Spring School for Immunology of the Deutsche Gesellschaft für Immunologie. Though retired meanwhile, he still gives introductory lectures at the Spring and Autumn School, and a lecture on Concepts in Immunology at Uni Greifswald.

Bibliographic Information

  • Book Title: Evolutionary Concepts in Immunology

  • Authors: Robert Jack, Louis Du Pasquier

  • DOI: https://doi.org/10.1007/978-3-030-18667-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-18666-1Published: 04 July 2019

  • Softcover ISBN: 978-3-030-18669-2Published: 14 August 2020

  • eBook ISBN: 978-3-030-18667-8Published: 13 June 2019

  • Edition Number: 1

  • Number of Pages: XVI, 145

  • Number of Illustrations: 2 b/w illustrations, 24 illustrations in colour

  • Topics: Immunology, Evolutionary Biology, Developmental Biology

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