Overview
- An updated perspective on cancer with a Development and Evolutionary perspective
- Hallmarks of Cancer structured in 2 main arms: tumor-autonomous vs non-autonomous traits
- Easy to read language, containing appealing illustrations, respecting the scientific accuracy
Part of the book series: Learning Materials in Biosciences (LMB)
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About this book
This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach.
The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed.
The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease
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Table of contents (10 chapters)
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Front Matter
Editors and Affiliations
About the editors
Professor Dr. Rita Fior teaches Molecular and Cell Biology of Cancer at the Faculty of Sciences in the University of Lisbon, Portugal. She is also a Principal Investigator at the Champalimaud Foundation, a renowned state-of-the-art center for Science. She has worked with Julian Lewis (Emeritus Scientist and Fellow of the Royal Society, CRUK).
Professor Dr. Rita Zilhão has been teaching for more than 20 years at the Faculty of Sciences in the University of Lisbon, Portugal. At this moment she is responsible for 3 courses: Genetic and Molecular Biology, Basics of Molecular Biology and Molecular and Cell Biology of Cancer. She is the coordinator of the Molecular and Genetic Biology Bachelor Program.
Professor Dr. Rita Zilhão has been teaching for more than 20 years at the Faculty of Sciences in the University of Lisbon, Portugal. At this moment she is responsible for 3 courses: Genetic and Molecular Biology, Basics of Molecular Biology and Molecular and Cell Biology of Cancer. She is the coordinator of the Molecular and Genetic Biology Bachelor Program.
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Bibliographic Information
Book Title: Molecular and Cell Biology of Cancer
Book Subtitle: When Cells Break the Rules and Hijack Their Own Planet
Editors: Rita Fior, Rita Zilhão
Series Title: Learning Materials in Biosciences
DOI: https://doi.org/10.1007/978-3-030-11812-9
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Softcover ISBN: 978-3-030-11811-2Published: 08 July 2019
eBook ISBN: 978-3-030-11812-9Published: 27 June 2019
Series ISSN: 2509-6125
Series E-ISSN: 2509-6133
Edition Number: 1
Number of Pages: IX, 216
Number of Illustrations: 71 illustrations in colour
Topics: Cancer Research, Human Genetics, Molecular Medicine, Cell Biology, Metabolomics