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Paleogenomics

Genome-Scale Analysis of Ancient DNA

  • Book
  • © 2019

Overview

Editors:
  1. Charlotte Lindqvist

    1. Department of Biological Sciences, University at Buffalo (SUNY), Buffalo, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Om P. Rajora

    1. Faculty of Forestry and Environmental Management, University of New Brunswick, Fredericton, Canada

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    You can also search for this editor in PubMed   Google Scholar

  • Paleogenomics is the first comprehensive book on paleogenomics, a rapidly evolving and fascinating field that investigates the genomes of ancient organisms and extinct species
  • Chapters in this book are contributed by some of the leaders in the field, covering a wide array of topics
  • This book provides insight into recent developments of concepts, technical advances and challenges, and promise of paleogenomics
  • This book reviews and synthesizes studies applying paleogenomics to a variety of organisms, from pathogens and plants to primates
  • This book analyzes current insights from paleogenomics into past environments, the evolution and adaptation of organisms to changing environmental conditions over a long period of time, and the processes of domestication and extinction

Part of the book series: Population Genomics (POGE)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Concepts, Technical Advances and Challenges

    1. Front Matter

      Pages 1-1
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    2. Technical Advances and Challenges in Genome-Scale Analysis of Ancient DNA

      • Tianying Lan, Charlotte Lindqvist
      Pages 3-29

    3. Paleoproteomics: An Introduction to the Analysis of Ancient Proteins by Soft Ionisation Mass Spectrometry

      • Michael Buckley
      Pages 31-52

    4. Ancient RNA

      • Oliver Smith, M. Thomas P. Gilbert
      Pages 53-74

    5. Ancient Epigenomics

      • Kristian Hanghøj, Ludovic Orlando
      Pages 75-111

  3. Paleogenomics Case Studies: From Ancient Pathogens to Primates

    1. Front Matter

      Pages 113-113
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    2. Ancient Pathogens Through Human History: A Paleogenomic Perspective

      • Stephanie Marciniak, Hendrik N. Poinar
      Pages 115-138

    3. Paleovirology: Viral Sequences from Historical and Ancient DNA

      • Kyriakos Tsangaras, Alex D. Greenwood
      Pages 139-162

    4. Reconstructing Past Vegetation Communities Using Ancient DNA from Lake Sediments

      • Laura Parducci, Kevin Nota, Jamie Wood
      Pages 163-187

    5. Archaeogenomics and Crop Adaptation

      • Robin G. Allaby, Oliver Smith, Logan Kistler
      Pages 189-203

    6. Herbarium Genomics: Plant Archival DNA Explored

      • Freek T. Bakker
      Pages 205-224

    7. Paleogenomics of Animal Domestication

      • Evan K. Irving-Pease, Hannah Ryan, Alexandra Jamieson, Evangelos A. Dimopoulos, Greger Larson, Laurent A. F. Frantz
      Pages 225-272

    8. Paleogenomic Inferences of Dog Domestication

      • Olaf Thalmann, Angela R. Perri
      Pages 273-306

    9. Of Cats and Men: Ancient DNA Reveals How the Cat Conquered the Ancient World

      • Eva-Maria Geigl, Thierry Grange
      Pages 307-324

    10. An Ancient DNA Perspective on Horse Evolution

      • Ludovic Orlando
      Pages 325-351

    11. Primate Paleogenomics

      • Krishna R. Veeramah
      Pages 353-373

    12. Structural Variants in Ancient Genomes

      • Skyler D. Resendez, Justin R. Bradley, Duo Xu, Omer Gokcumen
      Pages 375-391

    13. Genomics of Extinction

      • Johanna von Seth, Jonas Niemann, Love Dalén
      Pages 393-418

  4. Back Matter

    Pages 419-427
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Keywords

About this book

Advances in genome-scale DNA sequencing technologies have revolutionized genetic research on ancient organisms, extinct species, and past environments. When it is recoverable after hundreds or thousands of years of unintended preservation, “ancient DNA” (or aDNA) is often highly degraded, necessitating specialized handling and analytical approaches.  Paleogenomics defines the field of reconstructing and analyzing the genomes of historic or long-dead organisms, most often through comparison with modern representatives of the same or similar species. The opportunity to isolate and study paleogenomes has radically transformed many fields, spanning biology, anthropology, agriculture, and medicine. Examples include understanding evolutionary relationships of extinct species known only from fossils, the domestication of plants and animals, and the evolution and geographical spread of certain pathogens. This pioneering book presents a snapshot view of the history, current status, and future prospects of paleogenomics, taking a broad viewpoint that covers a range of topics and organisms to provide an up-to-date status of the applications, challenges, and promise of the field. This book is intended for a variety of readerships, including upper-level undergraduate and graduate students, professionals and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers.

Reviews

“This book is intended for a variety of readers, including upper-level undergraduate and graduate students, professionals, and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers. This well-written volume is for well-read undergraduate students, and is definitely a good read for graduate students and professionals.” (Lorin R. King, The Quarterly Review of Biology, Vol. 95 (4), December, 2020)

Editors and Affiliations

  • Department of Biological Sciences, University at Buffalo (SUNY), Buffalo, USA

    Charlotte Lindqvist

  • Faculty of Forestry and Environmental Management, University of New Brunswick, Fredericton, Canada

    Om P. Rajora

About the editors

Dr. Charlotte Lindqvist
Associate Professor

University at Buffalo (SUNY)
Department of Biological Sciences

Buffalo, NY
USA


Dr. Om P. Rajora
Professor
University of New Brunswick
Fredericton, NB E3C 5A3
Canada





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