Overview
- Offers cutting-edge methods for cancer gene profiling
- Includes methods for gene expression profiling and array CGH, as well as protein analysis
- Provides information about collecting clinical samples and their use in microdissection
Part of the book series: Methods in Molecular Biology (MIMB, volume 576)
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Table of contents (22 protocols)
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Front Matter
Keywords
About this book
Over the last few years, the methods for analyzing cancer-related genes on a molecular level have changed rapidly. The advent of incredible new technology, such as automated sequencing, has served as a catalyst for many advances in the area of gene profiling, and has enabled the research community to investigate populations of cells in a given tissue. Cancer Gene Profiling: Methods and Protocols examines the world of cancer gene profiling in light of these new advances, providing highly developed microarray techniques alongside modern methods for arraying tissues and proteomics. Chapters bring together the experiences of leading scientists in each method of profiling, providing a clear overview of the ground-breaking techniques used to perform these experiments effectively. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.
Comprehensive and state-of-the-art, Cancer Gene Profiling: Methods and Protocols is a fundamental guidebook for researchers in the field of cancer gene profiling, as well as for those individuals in the area of biomedical/translational research.
Reviews
From the reviews:
“The team of over 60 contributors put together an impressive compilation, covering a whole process of genetic analysis of cancer tissue … . Usefulness of the book is increased by the fact that most of the methods are optimized for real-life clinical tissue samples not just cell lines. … All in all, this book clearly demonstrated that the molecular methods used in the diagnosis and research of cancer, and of any other disease for that matter, entered the 21st century.” (J. Markus, Neoplasma, March, 2011)Editors and Affiliations
Bibliographic Information
Book Title: Cancer Gene Profiling
Book Subtitle: Methods and Protocols
Editors: Robert Grützmann, Christian Pilarsky
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-545-9
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2010
Hardcover ISBN: 978-1-934115-76-3Published: 06 November 2009
Softcover ISBN: 978-1-61779-659-3Published: 07 March 2012
eBook ISBN: 978-1-59745-545-9Published: 31 October 2009
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 452
Topics: Oncology, Cancer Research, Gene Expression