Abeta Peptide and Alzheimer's Disease
Celebrating a Century of Research
Editors: Barrow, Colin J., Small, David H. (Eds.)
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- About this book
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Abeta Peptide and Alzheimer’s Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer’s Disease (AD), shown by recent advances in genetics and brain biochemistry.
Written by leaders in the industrial and academic world specializing in this rapidly moving area, the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases, such as prion disease, Parkinson’s and Huntington’s.
This book will primarily be of interest to AD researchers and clinicians but also to researchers of other amyloid diseases.
- Table of contents (16 chapters)
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A Brief Introduction to the History of the β-Amyloid Protein (Aβ) of Alzheimer’s Disease
Pages 1-4
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The Aβcentric Pathway of Alzheimer’s Disease
Pages 5-36
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The Function of the Amyloid Precursor Protein Family
Pages 37-51
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The Involvement of Aβ in the Neuroinflammatory Response
Pages 52-82
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Amyloid β-Peptide(1-42), Oxidative Stress, and Alzheimer’s Disease
Pages 83-92
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Table of contents (16 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Abeta Peptide and Alzheimer's Disease
- Book Subtitle
- Celebrating a Century of Research
- Editors
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- Colin J. Barrow
- David H. Small
- Copyright
- 2007
- Publisher
- Springer-Verlag London
- Copyright Holder
- Springer-Verlag London
- eBook ISBN
- 978-1-84628-440-3
- DOI
- 10.1007/978-1-84628-440-3
- Hardcover ISBN
- 978-1-85233-961-6
- Softcover ISBN
- 978-1-4471-6234-6
- Edition Number
- 1
- Number of Pages
- XI, 298
- Topics
