- Covers, in great detail, electrochemical biosensor technology as applied to the neurosciences
- Explores the great progress in this field with in-depth methodologies
- Features tips from the experts, included to ensure optimal results
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- About this book
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For molecules that are not directly electroactive, it is necessary to modify a microelectrode by grafting polymeric or enzymatic membranes capable of translating a local concentration into an electrical current, which is a concept referred to as biosensing. In Microelectrode Biosensors, experts in the field cover the topic of electrochemical biosensor technology as applied to the neurosciences. The volume opens with a section addressing the specific issue of manufacturing biosensors that can be implanted in the central nervous system for neurotransmitter detection, and it then continues with sections on recent studies where biosensors have made a difference in bringing a new level of understanding of signaling mechanisms in neuroscience as well as recent developments in biosensor technology that have not yet been applied to implantable microelectrodes but may have great potential. Written for the Neuromethods series, this work contains the kind of detailed descriptions and implementation advice necessary to achieve successful results.
Focused and cutting-edge, Microelectrode Biosensors serves to inspire the wider neuroscience and physiology community to adopt these powerful methods in their own applications in order to move the field forward with the widespread advances that will most likely flow from the adoption of biosensing as part of the standard laboratory toolkit.
- Table of contents (17 chapters)
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Microelectrode Designs for Oxidase-Based Biosensors
Pages 3-25
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Microelectrode Array Fabrication and Optimization for Selective Neurochemical Detection
Pages 27-54
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The Advantage of Microelectrode Technologies for Measurement in Delicate Biological Environments Such as Brain Tissue
Pages 55-68
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Hexacyanoferrates as Mediators for Microelectrode Biosensors
Pages 69-93
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Enzyme Immobilization on Microelectrode Biosensors
Pages 95-114
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Table of contents (17 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Microelectrode Biosensors
- Editors
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- Stéphane Marinesco
- Nicholas Dale
- Series Title
- Neuromethods
- Series Volume
- 80
- Copyright
- 2013
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media, LLC
- eBook ISBN
- 978-1-62703-370-1
- DOI
- 10.1007/978-1-62703-370-1
- Hardcover ISBN
- 978-1-62703-369-5
- Softcover ISBN
- 978-1-4939-5901-3
- Series ISSN
- 0893-2336
- Edition Number
- 1
- Number of Pages
- XV, 387
- Topics