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Methods in Molecular Biology

Computational Toxicology

Volume II

Editors: Reisfeld, Brad, Mayeno, Arthur N. (Eds.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook 139,09 €
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  • ISBN 978-1-62703-059-5
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Hardcover 171,59 €
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Softcover 171,59 €
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About this book

Rapid advances in computer science, biology, chemistry, and other disciplines are enabling powerful new computational tools and models for toxicology and pharmacology. These computational tools hold tremendous promise for advancing applied and basic science, from streamlining drug efficacy and safety testing, to increasing the efficiency and effectiveness of risk assessment for environmental chemicals. Computational Toxicology was conceived to provide both experienced and new biomedical and quantitative scientists with essential background, context, examples, useful tips, and an overview of current developments in the field. This two-volume set serves as a resource to help introduce and guide readers in the development and practice of these tools to solve problems and perform analyses in this area.

Divided into six sections, Volume II covers a wide array of methodologies and topics. The volume begins by exploring the critical area of predicting toxicological and pharmacological endpoints, as well as approaches used in the analysis of gene, signaling, regulatory, and metabolic networks. The next section focuses on diagnostic and prognostic molecular indicators (biomarkers), followed by the application of modeling in the context of government regulatory agencies.  Systems toxicology approaches are also introduced. The volume closes with primers and background on some of the key mathematical and statistical methods covered earlier, as well as a list of other resources. Written in a format consistent with the successful Methods in Molecular Biology™ series where possible, chapters include introductions to their respective topics, lists of the necessary materials and software tools used, methods, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Computational Toxicology will allow motivated readers to participate in this exciting field and undertake a diversity of realistic problems of interest.

Table of contents (25 chapters)

Table of contents (25 chapters)

Buy this book

eBook 139,09 €
price for Spain (gross)
  • ISBN 978-1-62703-059-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 171,59 €
price for Spain (gross)
Softcover 171,59 €
price for Spain (gross)
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Bibliographic Information

Bibliographic Information
Book Title
Computational Toxicology
Book Subtitle
Volume II
Editors
  • Brad Reisfeld
  • Arthur N. Mayeno
Series Title
Methods in Molecular Biology
Series Volume
930
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
Distribution Rights
Distribution rights for India: Mehul Book Sales, Mumbai, India
eBook ISBN
978-1-62703-059-5
DOI
10.1007/978-1-62703-059-5
Hardcover ISBN
978-1-62703-058-8
Softcover ISBN
978-1-4939-6326-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 648
Topics