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Methods in Molecular Biology

Rational Drug Design

Methods and Protocols

Editors: Zheng, Yi (Ed.)

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  • Aids scientists in further study of rational drug design
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook 101,14 €
price for Spain (gross)
  • ISBN 978-1-62703-008-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 124,79 €
price for Spain (gross)
  • ISBN 978-1-62703-007-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 124,79 €
price for Spain (gross)
  • ISBN 978-1-4939-5900-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

Over the past  three decades there have been new developments in therapeutic drug design. In Rational Drug Design: Methods and Protocols,  expert researchers in the field detail many of the methodologies used to study rational drug design. These include methods such as virtual screening of chemical hits, rational lead discovery by high throughput screening, combinatorial and fragment based lead generation, peptide based drug discovery, and animal models of lead validation. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and practical, Rational Drug Design: Methods and Protocols seeks to aid scientists in the further study of rational drug design and future drug discovery.

Reviews

From the reviews:

“This book covers some of the tools and techniques involved in rational drug design with a series of case studies designed to act as a compendium of methods and protocols intended for readers to adopt or modify. … The book would therefore make interesting reading to any student or investigator looking to gain a wider appreciation of strategies and activities across different disciplines or unfamiliar projects in the early drug discovery phase as well as the primary target audience of organic/medicinal chemists and molecular biologists.” (Stefan Kavanagh, BTS Newsletter – The British Toxicology Society, Issue 43, Winter, 2013)

Table of contents (17 chapters)

Table of contents (17 chapters)
  • On Setting Up and Assessing Docking Simulations for Virtual Screening

    Biesiada, Jacek (et al.)

    Pages 1-16

  • Virtual Ligand Screening Combined with NMR to Identify Dvl PDZ Domain Inhibitors Targeting the Wnt Signaling

    Shan, Jufang (et al.)

    Pages 17-28

  • Rational Design of Rho GTPase-Targeting Inhibitors

    Shang, Xun (et al.)

    Pages 29-38

  • Rational Design of Peptide Ligands Against a Glycolipid by NMR Studies

    Tong, Wenyong (et al.)

    Pages 39-52

  • A Combinatorial Strategy for the Acquisition of Potent and Specific Protein Tyrosine Phosphatase Inhibitors

    Zhang, Sheng (et al.)

    Pages 53-65

Buy this book

eBook 101,14 €
price for Spain (gross)
  • ISBN 978-1-62703-008-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 124,79 €
price for Spain (gross)
  • ISBN 978-1-62703-007-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 124,79 €
price for Spain (gross)
  • ISBN 978-1-4939-5900-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Rational Drug Design
Book Subtitle
Methods and Protocols
Editors
  • Yi Zheng
Series Title
Methods in Molecular Biology
Series Volume
928
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
Distribution Rights
Distribution rights for India: Mehul Book Sales, Mumbai, India
eBook ISBN
978-1-62703-008-3
DOI
10.1007/978-1-62703-008-3
Hardcover ISBN
978-1-62703-007-6
Softcover ISBN
978-1-4939-5900-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 230
Number of Illustrations
36 b/w illustrations, 22 illustrations in colour
Topics