Prenatal Gene Therapy
Concepts, Methods, and Protocols
Editors: Coutelle, Charles, Waddington, Simon N. (Eds.)
Free Preview- Aims at applying gene therapy during preganancy for the prevention of human diseases
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
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- About this book
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The emerging field of prenatal gene therapy is founded on scientific and technical advances in fetal medicine, molecular biology and gene therapy. This preclinical research subject aims at applying gene therapy during pregnancy for the prevention of human diseases caused by early onset congenital or gestation related conditions. In Prenatal Gene Therapy: Concepts, Methods and Protocols, expert researchers in the field detail many of the protocols which are now commonly used to study gene therapy, fetal medicine and medical ethics. These include detailed protocols for vector production, for breeding and husbandry of the animal models, for the surgical procedures of gene delivery in large and small animals and for the methods of gene transfer analysis. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Thorough and intuitive, Prenatal Gene Therapy: Concepts, Methods and Protocols seeks to aid scientists in the further study of prenatal disease and gene therapy projects beyond the scope of fetal medicine.
- Table of contents (17 chapters)
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The Concept of Prenatal Gene Therapy
Pages 1-7
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Candidate Diseases for Prenatal Gene Therapy
Pages 9-39
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Vector Systems for Prenatal Gene Therapy: Choosing Vectors for Different Applications
Pages 41-53
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Vector Systems for Prenatal Gene Therapy: Principles of Adenovirus Design and Production
Pages 55-84
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Vector Systems for Prenatal Gene Therapy: Principles of Retrovirus Vector Design and Production
Pages 85-107
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Table of contents (17 chapters)
- Download Preface 1 PDF (60.1 KB)
- Download Sample pages 1 PDF (393.4 KB)
- Download Table of contents PDF (91.1 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Prenatal Gene Therapy
- Book Subtitle
- Concepts, Methods, and Protocols
- Editors
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- Charles Coutelle
- Simon N. Waddington
- Series Title
- Methods in Molecular Biology
- Series Volume
- 891
- Copyright
- 2012
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media, LLC.
- eBook ISBN
- 978-1-61779-873-3
- DOI
- 10.1007/978-1-61779-873-3
- Hardcover ISBN
- 978-1-61779-872-6
- Softcover ISBN
- 978-1-4939-5911-2
- Series ISSN
- 1064-3745
- Edition Number
- 1
- Number of Pages
- X, 392
- Number of Illustrations
- 26 b/w illustrations, 7 illustrations in colour
- Topics
