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  • © 2010

Cancer Nanotechnology

Methods and Protocols

  • Includes cutting-edge methods from leading experts in the field
  • Details nanoparticle platforms currently employed for cancer
  • Provides detailed protocols with notes written from extensive experience
  • Contains applications of nanotechnology for cancer imaging
  • Elucidates delivery and targeting of nanomaterials for cancer
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 624)

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Table of contents (26 protocols)

  1. Front Matter

    Pages i-xiii
  2. What Is Cancer Nanotechnology?

    • Stephen R. Grobmyer, Nobutaka Iwakuma, Parvesh Sharma, Brij M. Moudgil
    Pages 1-9
  3. Nanoparticle Characterization for Cancer Nanotechnology and Other Biological Applications

    • Scott C. Brown, Maria Palazuelos, Parvesh Sharma, Kevin W. Powers, Stephen M. Roberts, Stephen R. Grobmyer et al.
    Pages 39-65
  4. Multimodal Nanoparticulate Bioimaging Contrast Agents

    • Parvesh Sharma, Amit Singh, Scott C. Brown, Niclas Bengtsson, Glenn A. Walter, Stephen R. Grobmyer et al.
    Pages 67-81
  5. Gold Nanocages for Cancer Imaging and Therapy

    • Leslie Au, Jingyi Chen, Lihong V. Wang, Younan Xia
    Pages 83-99
  6. Nanoshells for Photothermal Cancer Therapy

    • Jennifer G. Morton, Emily S. Day, Naomi J. Halas, Jennifer L. West
    Pages 101-117
  7. Gold Nanorods: Multifunctional Agents for Cancer Imaging and Therapy

    • Alexander Wei, Alexei P. Leonov, Qingshan Wei
    Pages 119-130
  8. Fluorescent Silica Nanoparticles for Cancer Imaging

    • Swadeshmukul Santra
    Pages 151-162
  9. Polymeric Nanoparticles for Drug Delivery

    • Juliana M. Chan, Pedro M. Valencia, Liangfang Zhang, Robert Langer, Omid C. Farokhzad
    Pages 163-175
  10. Synthesis, Characterization, and Functionalization of Gold Nanoparticles for Cancer Imaging

    • Gary A. Craig, Peter J. Allen, Michael D. Mason
    Pages 177-193
  11. Identification of Pancreatic Cancer-Specific Cell-Surface Markers for Development of Targeting Ligands

    • David L. Morse, Galen Hostetter, Yoganand Balagurunathan, Robert J. Gillies, Haiyong Han
    Pages 195-210
  12. Preparation and Characterization of Doxorubicin Liposomes

    • Guoqin Niu, Brian Cogburn, Jeffrey Hughes
    Pages 211-219
  13. PEGylated Nanocarriers for Systemic Delivery

    • N.K. Jain, Manoj Nahar
    Pages 221-234
  14. Nanoparticle–Aptamer Conjugates for Cancer Cell Targeting and Detection

    • M. Carmen Estévez, Yu-Fen Huang, Huaizhi Kang, Meghan B. O’Donoghue, Suwussa Bamrungsap, Jilin Yan et al.
    Pages 235-248
  15. Targeting of Nanoparticles: Folate Receptor

    • Sumith A. Kularatne, Philip S. Low
    Pages 249-265
  16. Magnetic Aerosol Targeting of Nanoparticles to Cancer: Nanomagnetosols

    • Carsten Rudolph, Bernhard Gleich, Andreas W. Flemmer
    Pages 267-280
  17. LHRH-Targeted Nanoparticles for Cancer Therapeutics

    • Tamara Minko, Mahesh L. Patil, Min Zhang, Jayant J. Khandare, Maha Saad, Pooja Chandna et al.
    Pages 281-294

About this book

Early detection of cancer at the cellular level, even before anatomic anomalies are visible, is critical to more efficacious and cost effective diagnosis and therapeutic advances. In Cancer Nanotechnology: Methods and Protocols, an international panel of experts provide the most recent, cutting-edge, "how-to" approaches developed and employed by researchers in a variety of disciplines to identify cancer specific biomarkers, construct suitable multifunctional targeted nanostructure platforms, along with enhanced imaging and therapeutic applications. Covering such topics as multifunctional and multimodal nanoparticles, nanoparticle mediated cancer theranostics, molecular targets for cancer nanotechnology, and nanoparticles for non-invasive image-guided cancer therapy, the volume addresses the key challenges of the field today, specifically targeted and localized delivery of the drugs. As a volume in the highly successful Methods in Molecular Biology™ series, the protocols chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Cancer Nanotechnology: Methods and Protocols integrates cancer biology, clinical oncology, molecular cancer imaging, materials science and chemical engineering, biomedical engineering, toxicology, computer science, electrical engineering, chemistry, physics, and mathematics in order to achieve the vital goals of nanotechnology-mediated early cancer detection and more efficacious and less toxic therapies for these devastating diseases.

Reviews

From the reviews:

“This well-illustrated book provides authoritative and cutting-edge reviews on topics such as multifunctional and multimodal nanoparticles, nanoparticle-mediated cancer theranostics, molecular targets for cancer nanotechnology, nanoparticles for noninvasive image-guided cancer therapy, and targeted and localized delivery of the drugs. … It is intended for both established researchers and those embarking on their maiden research voyage in the field. It will be extremely useful for established investigators, students, clinical oncologists, and others interested in the field of cancer nanotechnology.” (Omer Iqbal, Doody’s Review Service, August, 2010)

Editors and Affiliations

  • Dept. Surgery, University of Florida, Gainesville, USA

    Stephen R. Grobmyer

  • ERC - Engineering Research Center, University of Florida, Gainesville, USA

    Brij M. Moudgil

Bibliographic Information

  • Book Title: Cancer Nanotechnology

  • Book Subtitle: Methods and Protocols

  • Editors: Stephen R. Grobmyer, Brij M. Moudgil

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-60761-609-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2010

  • Hardcover ISBN: 978-1-60761-608-5Published: 16 March 2010

  • Softcover ISBN: 978-1-4939-6120-7Published: 23 August 2016

  • eBook ISBN: 978-1-60761-609-2Published: 10 March 2010

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XIII, 396

  • Topics: Oncology, Cancer Research, Laboratory Medicine

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access