Molecular Profiling
Methods and Protocols
Editors: Espina, Virginia, Liotta, Lance (Eds.)
Free Preview- Emphasis placed on tissue based molecular profiling, not covered in pathology text books
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
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- About this book
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The next revolution in molecular medicine is the application of molecular profiling to individualized patient therapy. Molecular profiling technology has advanced dramatically, particularly in the field of cancer tissue biomarkers. It is now possible to gather complex genomic and proteomic information from a routine clinical needle biopsy or surgical specimen. In Molecular Profiling : Methods and Protocols, expert researchers in the field focus on the entire process from discovery to commercialization, with practical guides that are not limited to experimental methods. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, as well as essays and guidelines for grants, patents, and commercialization of products related to molecular profiling.
Authoritative and practical, Molecular Profiling: Methods and Protocols seeks to aid scientists in understanding the latest advancements in genomics, proteomics, imagining, and bioinformatics. - Reviews
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From the reviews:
“This informative book combines genomics, proteomics, and bioinformatics with experimental protocols and detailed discussions regarding future challenges in commercialization and practical use in the field with an emphasis on tissue-based molecular profiling. … readers can use this as a practical guide at the laboratory bench as well as in the boardroom. The book is written for scientists, pathologists, oncologists, biotechnologists, residents, medical students, and nurses involved in clinical trial research. … This will be a valuable tool for those involved in clinical trial research.” (Omer Iqbal, Doody’s Book Reviews, April, 2012)
- Table of contents (28 chapters)
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Tumor Staging and Grading: A Primer
Pages 1-18
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Clinical Trial Design in the Age of Molecular Profiling
Pages 19-34
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Personalized Medicine: Ethics for Clinical Trials
Pages 35-48
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Reduction of Preanalytical Variability in Specimen Procurement for Molecular Profiling
Pages 49-57
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The Human Side of Cancer Biobanking
Pages 59-77
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Table of contents (28 chapters)
- Download Preface 1 PDF (90.3 KB)
- Download Sample pages 1 PDF (453.7 KB)
- Download Table of contents PDF (92.9 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Molecular Profiling
- Book Subtitle
- Methods and Protocols
- Editors
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- Virginia Espina
- Lance Liotta
- Series Title
- Methods in Molecular Biology
- Series Volume
- 823
- Copyright
- 2012
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media, LLC
- eBook ISBN
- 978-1-60327-216-2
- DOI
- 10.1007/978-1-60327-216-2
- Hardcover ISBN
- 978-1-60327-215-5
- Softcover ISBN
- 978-1-4939-5684-5
- Series ISSN
- 1064-3745
- Edition Number
- 1
- Number of Pages
- XIII, 447
- Topics
