Overview
- Editors:
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Richard J. P. Cannell
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Glaxo Wellcome Research & Development, Stevenage, UK
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Table of contents (15 protocols)
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- Ed Venkat, Srinivas Kothandaraman
Pages 91-109
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- Gino M. Salituro, Claude Dufresne
Pages 111-140
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- Simon Gibbons, Alexander I. Gray
Pages 209-245
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- Norman Shankland, Alastair J. Florence, Richard J. P. Cannell
Pages 261-278
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- Frank Van Middlesworth, Richard J. P. Cannell
Pages 279-327
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- Gloria L. Silva, Ik-Soo Lee, A. Douglas Kinghorn
Pages 343-363
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- Michael S. Verrall, Stephen R. C. Warr
Pages 409-424
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Back Matter
Pages 465-473
About this book
Researchers from both industry and academia present in detail techniques for the extraction and isolation of natural products of all classes. These experienced experimentalists describe a wide array of methodologies, including basic chromatography, ion-exchange methods, HPLC, countercurrent and planar chromatography, SFE, and crystallization. They also address the specific problems involved in working with plants, marine organisms, water-soluble compounds, scale-up, dereplication and partial identification, and follow-up of a natural product lead. For the less-experienced they offer hands-on advice-using real examples-about how to approach an extraction in general, when and why to apply a particular technique, how to carry out the methods described, and how to modify conditions according to the compound being isolated.
Reviews
". . . offers extensive help in the selection of a suitable methodology. . .an excellent aid. . .closes a painfully evident gap in the selection of monographs on natural products chemistry. . .warmly recommended to anyone interested in the isolation of natural products."-Angewandte Chemie
". . .a very good general reference that concentrates a considerable amount of useful practical information. . .well worth considering as a reference for graduate students or other researchers who might need to familiarize themselves with the intricacies of the subject."-Journal of Natural Products
Editors and Affiliations
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Glaxo Wellcome Research & Development, Stevenage, UK
Richard J. P. Cannell
