Hepatocyte Transplantation
Methods and Protocols
Editors: Dhawan, Anil, Hughes, Robin D. (Eds.)
Free Preview- Brings together all the methodology needed to perform human hepatocyte transplantation for the first time in one volume
- Key researchers cover all aspects of hepatocyte transplantation from bench to bedside
- Provides a practical basis for evaluating stem cell-derived hepatocytes for the treatment of liver disease in the future
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- About this book
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Due to its efficacy in animal models, cellular therapy using human hepatocytes is being evaluated worldwide as an alternative to organ transplantation in patients with liver-based metabolic disease and acute liver failure. In Hepatocyte Transplantation: Methods and Protocols, an international panel of experts provide up-to-date laboratory and clinical techniques covering the many key areas necessary for successful transplantation, such as cryopreservation, quality assurance, detection of cell engraftment, and the future of the field with the development of foetal hepatoblasts and stem cell derived hepatocytes. Written in the highly successful Methods in Molecular Biology™ series format, the chapters in this volume present brief introductions to the material, lists of the necessary materials and reagents, readily reproducible, step-by-step laboratory protocols, and Notes sections which highlight tips on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting-edge, Hepatocyte Transplantation: Methods and Protocols is an ideal guide for researchers setting out in the rapidly progressing field of hepatocyte transplantation, as well as those who already have experience with this new therapy for liver disease.
- Table of contents (18 chapters)
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Human Hepatocyte Transplantation Overview
Pages 1-16
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Isolation of Human Hepatocytes
Pages 17-23
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An Optimised Method for Cryopreservation of Human Hepatocytes
Pages 25-34
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Liver Cell Culture Techniques
Pages 35-46
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In Vitro Assays for Induction of Drug Metabolism
Pages 47-58
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Table of contents (18 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Hepatocyte Transplantation
- Book Subtitle
- Methods and Protocols
- Editors
-
- Anil Dhawan
- Robin D. Hughes
- Series Title
- Methods in Molecular Biology
- Series Volume
- 481
- Copyright
- 2009
- Publisher
- Humana Press
- Copyright Holder
- Humana Press
- eBook ISBN
- 978-1-59745-201-4
- DOI
- 10.1007/978-1-59745-201-4
- Hardcover ISBN
- 978-1-58829-883-6
- Series ISSN
- 1064-3745
- Edition Number
- 1
- Number of Pages
- XVII, 231
- Topics
