Medical Intelligence Unit

Clinical Benefits of Leukodepleted Blood Products

Editors: Sweeney, Joseph (Ed.)

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eBook 85,59 €
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  • ISBN 978-3-662-26538-3
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Softcover 103,99 €
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About this book

Joseph Sweeney, Andrew Heaton he presence of allogeneic leukocytes in blood products received little T attention until the mid-1950s when these "passenger" cells were im­ plicated in the etiology of febrile transfusion reactions, and early strate­ gies based on centrifugation were developed to effect their removal. In recent decades and, particularly in the past five years, there has been an accumulation of literature implicating leukocytes in a wide variety of undesirable reactions to blood transfusion. White cells are the least numerous of the cellular elements in blood and ratios of white cells to platelets and white cells to red cells are ap­ proximately 1:15 to 1:1000 respectively. This ratio is maintained in whole blood, but may be altered slightly in the process of component prepara­ tion. Any production or processing step which intentionally decreases this ratio will result in a product which can be described as white cell depleted. It has, however, become more common to define the outcome as a residual white cell content, rather than a decrease in cellular ratios, although the latter makes more sense on theoretical grounds, since deple­ tion of white cells needs to be put in the context of any unintentional loss of red cells or platelets. The end result of this intentional processing step, therefore, is generally expressed as the residual absolute number of white cells or as the degree of difference in white cell content, the latter expressed as either a percentage change or as a logarithmic reduction.

Table of contents (14 chapters)

Table of contents (14 chapters)

Buy this book

eBook 85,59 €
price for Spain (gross)
  • ISBN 978-3-662-26538-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover 103,99 €
price for Spain (gross)
  • ISBN 978-1-57059-122-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Clinical Benefits of Leukodepleted Blood Products
Editors
  • Joseph Sweeney
Series Title
Medical Intelligence Unit
Copyright
1995
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-26538-3
DOI
10.1007/978-3-662-26538-3
Softcover ISBN
978-1-57059-122-8
Edition Number
1
Number of Pages
X, 198
Number of Illustrations
15 b/w illustrations
Topics