Methods in Molecular Biology

High-Throughput Metabolomics

Methods and Protocols

Editors: D'Alessandro, Angelo (Ed.)

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  • Includes cutting-edge techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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  • ISBN 978-1-4939-9236-2
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Hardcover 176,79 €
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About this book

This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

Table of contents (27 chapters)

Table of contents (27 chapters)
  • Sample Preparation and Reporting Standards for Metabolomics of Adherent Mammalian Cells

    Pages 3-12

    Hayton, Sarah (et al.)

  • High-Throughput Metabolomics: Isocratic and Gradient Mass Spectrometry-Based Methods

    Pages 13-26

    Nemkov, Travis (et al.)

  • High-Throughput Metabolomics Based on Direct Mass Spectrometry Analysis in Biomedical Research

    Pages 27-38

    González-Domínguez, Raúl (et al.)

  • Traveling Wave Ion Mobility Mass Spectrometry: Metabolomics Applications

    Pages 39-53

    Paglia, Giuseppe (et al.)

  • Capillary Electrophoresis Mass Spectrometry as a Tool for Untargeted Metabolomics

    Pages 55-77

    López-Gonzálvez, Ángeles (et al.)

Buy this book

eBook 142,79 €
price for Spain (gross)
  • ISBN 978-1-4939-9236-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 176,79 €
price for Spain (gross)
  • ISBN 978-1-4939-9235-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
High-Throughput Metabolomics
Book Subtitle
Methods and Protocols
Editors
  • Angelo D'Alessandro
Series Title
Methods in Molecular Biology
Series Volume
1978
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-9236-2
DOI
10.1007/978-1-4939-9236-2
Hardcover ISBN
978-1-4939-9235-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XV, 459
Number of Illustrations
20 b/w illustrations, 63 illustrations in colour
Topics