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Methods in Molecular Biology

Non-Natural Nucleic Acids

Methods and Protocols

Editors: Shank, Nathaniel (Ed.)

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  • Includes cutting-edge techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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eBook 139,09 €
price for Spain (gross)
  • ISBN 978-1-4939-9216-4
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Hardcover 176,79 €
price for Spain (gross)
  • ISBN 978-1-4939-9215-7
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  • Usually dispatched within 3 to 5 business days.
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About this book

This volume provides relevant synthetic strategies, incorporation, and applications of non-natural nucleic acids. Chapters detail monomer synthesis, oligomer synthesis/construction, and applications allowing researchers to explore and determine which methodology or methodologies are relevant to their needs.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and cutting-edge, Non-Natural Nucleic Acids: Methods and Protocols aims to serve as a guide for researchers exploring their own inquiries and to provide a springboard for new endeavors.

Table of contents (19 chapters)

Table of contents (19 chapters)
  • Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs

    Pages 1-13

    Diafa, Stella (et al.)

  • Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites: 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine and 2′-Deoxycytidine

    Pages 15-25

    An, Na (et al.)

  • Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue

    Pages 27-37

    Mei, Hui (et al.)

  • Synthesis of Base-Modified dNTPs Through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA

    Pages 39-57

    Ménová, Petra (et al.)

  • 2′-C,4′-C-Ethyleneoxy-Bridged 2′-Deoxyribonucleic Acids (EoDNAs) with Thymine Nucleobases: Synthesis, Duplex-Forming Ability, and Enzymatic Stability

    Pages 59-89

    Osawa, Takashi (et al.)

Buy this book

eBook 139,09 €
price for Spain (gross)
  • ISBN 978-1-4939-9216-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 176,79 €
price for Spain (gross)
  • ISBN 978-1-4939-9215-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Non-Natural Nucleic Acids
Book Subtitle
Methods and Protocols
Editors
  • Nathaniel Shank
Series Title
Methods in Molecular Biology
Series Volume
1973
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-9216-4
DOI
10.1007/978-1-4939-9216-4
Hardcover ISBN
978-1-4939-9215-7
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 315
Number of Illustrations
54 b/w illustrations, 41 illustrations in colour
Topics