Nutritional and Toxicological Significance of Enzyme Inhibitors in Foods
Authors: Friedman, Mendel
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- About this book
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Soybean protei ns are wi de 1 y used inhuman foods ina vari ety of forms, including baby formulas, flour, soy protein concentrates, soy protein isolates, soy sauces, textured soy fibers, and tofu. The presence of inhibitors of digestive enzymes in soy proteins impairs nutritional quality and possible safety of this impportant legume. Normal processing conditions based on the use of heat do not completely inactivate these inhibitors, so that residual amounts of plant protease inhibitors are consumed by animals and man. Inhibitors of digestive enzymes are present not only in legumes, such as soybeans, lima beans, and kidney beans, but also in nearly all plant foods, including cereals and potatoes, albeit in much smaller amounts. The antinutritional effects of inhibitors of proteolytic enzymes have been widely studied and can be ameliorated by processing and/or sulfur amino acid fortification. A more urgent concern is reports that rats fed diets containing even low levels of soybean-derived inhibitors, which are found in foods such as soy-based baby formulas, may develop over their lifespan pancreatic lesions leading eventually to neoplasia or tumor formation. On the other hand, recent stUdies suggest that certain enzyme inhibitors from plant foods may prevent cancer formation in other tissues. A key question, therefore, is whether inhibitors from plant foods constitute a human health hazard.
- Table of contents (31 chapters)
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Protein Inhibitors of Serine Proteinases — Mechanism and Classification
Pages 1-17
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The Biological Functions and Physiological Effects of Ingested Inhibitors of Digestive Reactions
Pages 19-31
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Safety of Trypsin Inhibitors in the Diet: Effects on the Rat Pancreas of Long-Term Feeding of Soy Flour and Soy Protein Isolate
Pages 33-79
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Dose Effects of Raw Soyabean Flour on Pancreatic Growth
Pages 81-89
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Enhancement of Pancreatic Carcinogenesis by Raw Soy Protein Isolate: Quantitative Rat Model and Nutritional Considerations
Pages 91-107
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Table of contents (31 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Nutritional and Toxicological Significance of Enzyme Inhibitors in Foods
- Authors
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- Mendel Friedman
- Series Title
- Advances in Experimental Medicine and Biology
- Series Volume
- 199
- Copyright
- 1986
- Publisher
- Springer US
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4757-0022-0
- DOI
- 10.1007/978-1-4757-0022-0
- Softcover ISBN
- 978-1-4757-0024-4
- Series ISSN
- 0065-2598
- Edition Number
- 1
- Number of Pages
- XI, 572
- Topics
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