Overview
- Discusses extensively the science of extrusion technology
- Brings together all technical information necessary to develop and market pharmaceutical dosage forms
- Provides the basic principles and fundamentals of extrusion technology
- Includes supplementary material: sn.pub/extras
Part of the book series: AAPS Advances in the Pharmaceutical Sciences Series (AAPS, volume 9)
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Table of contents (19 chapters)
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Introduction and Equipment
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Excipients
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Formulation Design
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Applications
Keywords
About this book
Editors and Affiliations
About the editors
Dr. Michael A. Repka is Chair and Professor of the Department of Pharmaceutics at The University of Mississippi, as well as Director of the Pii Center for Pharmaceutical Technology. Dr. Repka joined the faculty at Ole Miss after receiving his Ph.D. from The University of Texas College of Pharmacy and founded a pharmaceutical research/development company that specializes in drug delivery. His research interests include oral transmucosal and transdermal/trans-nail delivery systems, as well as other novel dosage forms. Many of these systems are directed toward the solubilization and delivery of poorly soluble bioactives via Hot Melt Extrusion technology, which is a primary focus of his research. Dr. Repka’s most important scientific accomplishments involve the advancement of melt extrusion technology. He has established himself as an expert in this major pharmaceutical processing field through his numerous peer-reviewed publications, presentations and scientific talks.
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Dr. Nigel Langley is currently Head of Marketing and Technical Sales at BASF Corporation where he is responsible for the promotion and technical support for BASF’s Pharmaceutical excipients and APIs to the Pharmaceutical Industry in North America. He has a strong interest in solubilization including Hot Melt Extrusion. He received his PhD in Liquid Crystals from Hull University, UK and an MBA from Leeds University, UK. Prior to joining BASF he worked for Croda International in UK, Japan and USA.
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Dr. James DiNunzio is currently an Associate Principal Scientist in the Formulation & Basic Pharmaceutical Sciences Group at Merck & Co., Inc. where he serves as a member of the Hot Melt Extrusion Technology Development Team. He received his Ph.D. in Pharmacy from the University of Texas at Austin and holds M.S. and B.S. in Chemical Engineering from Columbia University and SUNY Buffalo, respectively. Prior to joining Merck, heserved as Senior Scientist at Hoffmann-La Roche where he was responsible for the development of enabled formulations using hot melt extrusion.   He has also held scientific positions at PharmaForm, LLC and Forest Laboratories. With over seven years of industry experience, his research interests include formulation design of amorphous dispersions, development of controlled release products using melt extrusion, continuous manufacturing and engineering of directly shaped drug products.Bibliographic Information
Book Title: Melt Extrusion
Book Subtitle: Materials, Technology and Drug Product Design
Editors: Michael A. Repka, Nigel Langley, James DiNunzio
Series Title: AAPS Advances in the Pharmaceutical Sciences Series
DOI: https://doi.org/10.1007/978-1-4614-8432-5
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: American Association of Pharmaceutical Scientists 2013
Hardcover ISBN: 978-1-4614-8431-8Published: 11 October 2013
Softcover ISBN: 978-1-4939-5185-7Published: 23 August 2016
eBook ISBN: 978-1-4614-8432-5Published: 11 October 2013
Series ISSN: 2210-7371
Series E-ISSN: 2210-738X
Edition Number: 1
Number of Pages: XII, 474
Number of Illustrations: 141 b/w illustrations, 125 illustrations in colour
Topics: Biomedicine general, Pharmaceutical Sciences/Technology