Primates, Pathogens, and Evolution
Editors: Brinkworth, Jessica F., Pechenkina, Kate (Eds.)
Free Preview- · Integrates research from a broad range of fields on primate-pathogen molecular interactions, primate immune function, and primate-pathogen co-evolution
- · Provides a sound base of knowledge for future investigation of human and non-human primate evolution, immunity, and disease
- · Allows the specialist and educated lay-reader to understand and critically evaluate current data on differences in the molecular mechanics of primate immune response, pathogen-mediated primate evolution, and primate health
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- About this book
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The immune systems of human and non-human primates have diverged over time, such that some species differ considerably in their susceptibility, symptoms, and survival of particular infectious diseases. Variation in primate immunity is such that major human pathogens - such as immunodeficiency viruses, herpesviruses and malaria-inducing species of Plasmodium - elicit striking differences in immune response between closely related species and within primate populations. These differences in immunity are the outcome of complex evolutionary processes that include interactions between the host, its pathogens and symbiont/commensal organisms. The success of some pathogens in establishing persistent infections in humans and other primates has been determined not just by the molecular evolution of the pathogen and its interactions with the host, but also by the evolution of primate behavior and ecology, microflora, immune factors and the evolution of other biological systems.
To explore how interactions between primates and their pathogens have shaped their mutual molecular evolution, Primates, Pathogens and Evolution brings together research that explores comparative primate immune function, the emergence of major and neglected primate diseases, primate-microorganism molecular interactions, and related topics. This book will be of interest to anyone curious as to why infectious diseases manifest differently in humans and their closest relatives. It will be of particular interest to scholars specializing in human and non-human primate evolution, epidemiology and immunology, and disease ecology. Primates, Pathogens and Evolution offers an overview and discussion of current findings on differences in the molecular mechanics of primate immune response, as well as on pathogen-mediated primate evolution and human and non-human primate health.
- Table of contents (13 chapters)
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Primates, Pathogens and Evolution: An Introduction
Pages 1-14
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Vertebrate Immune System Evolution and Comparative Primate Immunity
Pages 17-64
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Genetic Variation in the Immune System of Old World Monkeys: Functional and Selective Effects
Pages 65-90
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Toll-Like Receptor Function and Evolution in Primates
Pages 91-116
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Impact of Natural Selection Due to Malarial Disease on Human Genetic Variation
Pages 117-160
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Table of contents (13 chapters)
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Bibliographic Information
- Bibliographic Information
-
- Book Title
- Primates, Pathogens, and Evolution
- Editors
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- Jessica F. Brinkworth
- Kate Pechenkina
- Series Title
- Developments in Primatology: Progress and Prospects
- Copyright
- 2013
- Publisher
- Springer-Verlag New York
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4614-7181-3
- DOI
- 10.1007/978-1-4614-7181-3
- Hardcover ISBN
- 978-1-4614-7180-6
- Softcover ISBN
- 978-1-4899-9479-0
- Series ISSN
- 1574-3489
- Edition Number
- 1
- Number of Pages
- X, 428
- Topics
