Neural-Immune Interactions in Brain Function and Alcohol Related Disorders
Editors: Cui, Changhai, Grandison, Lindsey, Noronha, Antonio (Eds.)
Free Preview- Provides a comprehensive overview on neuroimmune mechanisms mediating changes in brain function and behavior associated with alcohol drinking
- Combines emerging knowledge on neural-immune interactions with key discoveries in alcohol research
- First book to focus on the the interactions between alcohol and the neuroimmune system
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- About this book
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Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and an altered neuroimmune profile. This book integrates emerging knowledge on neural-immune interactions with key discoveries in alcohol research and provides a comprehensive overview of neural-immune interactions in brain function and behavior associated with alcohol use disorders. While Neural–Immune Interaction in Brain Function and Alcohol Related Disorders focuses on neural-immune interactions in areas directly related to alcohol use disorders, it is not intended to be all inclusive. Several areas, including sleep disorders, pain, and cholinergic anti-inflammatory pathways, are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts.
- Table of contents (18 chapters)
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An Introduction to CNS-Resident Microglia: Definitions, Assays, and Functional Roles in Health and Disease
Pages 3-29
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Astrocyte–Neuron Communications
Pages 31-64
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Neuroimmune Modulation of Synaptic Function
Pages 65-94
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Neuroimaging and Clinical Studies on Brain–Immune Interactions
Pages 95-132
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Mechanisms of Stress-Dependent Neuroinflammation and Their Implications for Understanding Consequences of Alcohol Exposure
Pages 133-166
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Table of contents (18 chapters)
- Download Preface 1 PDF (141 KB)
- Download Sample pages 1 PDF (327.3 KB)
- Download Table of contents PDF (141 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Neural-Immune Interactions in Brain Function and Alcohol Related Disorders
- Editors
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- Changhai Cui
- Lindsey Grandison
- Antonio Noronha
- Copyright
- 2013
- Publisher
- Springer US
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4614-4729-0
- DOI
- 10.1007/978-1-4614-4729-0
- Hardcover ISBN
- 978-1-4614-4728-3
- Softcover ISBN
- 978-1-4899-9578-0
- Edition Number
- 1
- Number of Pages
- VIII, 588
- Topics
