Computational Modeling of Biological Systems
From Molecules to Pathways
Editors: Dokholyan, Nikolay V (Ed.)
Free Preview- Reviews established modeling approaches of biological systems across multiple length and time scales from molecules to cells
- Covers recent and emerging computational techniques in modelling biological systems
- Provides a fresh outlook on the topic by covering multiscale modelling and includes a section on molecular evolution
- Can be used as a guide for selecting methods for studying biological systems
Buy this book
- About this book
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Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant systems.
- About the authors
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Dr. Nikolay Dokholyan joined the Department of Biochemistry and Biophysics in the University of North Carolina at Chapel Hill, School of Medicine as an Assistant Professor. In 2008, Dr. Dokholyan was promoted as Associate Professor. Dr. Dokholyan is currently the Director of the Center for Computational and Systems Biology and the Graduate Director of the Program in Molecular and Cellular Biophysics at UNC.
- Table of contents (15 chapters)
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Introduction to Molecular Dynamics: Theory and Applications in Biomolecular Modeling
Pages 3-30
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The Many Faces of Structure-Based Potentials: From Protein Folding Landscapes to Structural Characterization of Complex Biomolecules
Pages 31-54
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Discrete Molecular Dynamics Simulation of Biomolecules
Pages 55-73
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Small Molecule Docking from Theoretical Structural Models
Pages 75-95
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Homology Modeling: Generating Structural Models to Understand Protein Function and Mechanism
Pages 97-116
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Table of contents (15 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Computational Modeling of Biological Systems
- Book Subtitle
- From Molecules to Pathways
- Editors
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- Nikolay V Dokholyan
- Series Title
- Biological and Medical Physics, Biomedical Engineering
- Copyright
- 2012
- Publisher
- Springer-Verlag New York
- Copyright Holder
- Springer Science+Business Media, LLC
- eBook ISBN
- 978-1-4614-2146-7
- DOI
- 10.1007/978-1-4614-2146-7
- Hardcover ISBN
- 978-1-4614-2145-0
- Softcover ISBN
- 978-1-4899-8750-1
- Series ISSN
- 1618-7210
- Edition Number
- 1
- Number of Pages
- VI, 366
- Topics
