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Molecular Biology of DNA Methylation

  • Book
  • © 1985

Overview

Authors:
  1. Roger L. P. Adams

    1. Department of Biochemistry, University of Glasgow, Glasgow, UK

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    You can also search for this author in PubMed   Google Scholar

  2. Roy H. Burdon

    1. Department of Bioscience and Biotechnology, University of Strathclyde, Glasgow, UK

    View author publications

    You can also search for this author in PubMed   Google Scholar

Part of the book series: Springer Series in Molecular and Cell Biology (SSMOL)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Introduction

    • Roger L. P. Adams, Roy H. Burdon
    Pages 1-8

  3. DNA Methylation in the Cell

    • Roger L. P. Adams, Roy H. Burdon
    Pages 9-18

  4. DNA Structure and the Effect of Methylation

    • Roger L. P. Adams, Roy H. Burdon
    Pages 19-29

  5. S-Adenosyl-L-methionine—Donor of Methyl Groups

    • Roger L. P. Adams, Roy H. Burdon
    Pages 31-41

  6. The Methylation Machinery: DNA Methyltransferases

    • Roger L. P. Adams, Roy H. Burdon
    Pages 43-71

  7. The Function of DNA Methylation in Bacteria and Phage

    • Roger L. P. Adams, Roy H. Burdon
    Pages 73-87

  8. Methylation in Higher Eukaryotes

    • Roger L. P. Adams, Roy H. Burdon
    Pages 89-114

  9. Methylation and Its Relationship with Transcription

    • Roger L. P. Adams, Roy H. Burdon
    Pages 115-161

  10. X-Chromosome Inactivation

    • Roger L. P. Adams, Roy H. Burdon
    Pages 163-169

  11. DNA Methylation and Cancer

    • Roger L. P. Adams, Roy H. Burdon
    Pages 171-174

  12. Variations on a Theme: Patterns of Methylation in Protista, Fungi, Plants, and Animals

    • Roger L. P. Adams, Roy H. Burdon
    Pages 175-190

  13. Has DNA a Role in the Control of Transcription?

    • Roger L. P. Adams, Roy H. Burdon
    Pages 191-200

  14. Other Possible Functions of Eukaryotic DNA Methylation

    • Roger L. P. Adams, Roy H. Burdon
    Pages 201-206

  15. DNA Methylation in Perspective—A Summing Up

    • Roger L. P. Adams, Roy H. Burdon
    Pages 207-210

  16. Back Matter

    Pages 211-247
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Keywords

About this book

During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which in­ formation was transmitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramati­ cally different. We have an almost bewildering variety of information detailing many different aspects of life at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for replicating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macromolecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller mole­ cules work together to provide the molecular setting of living systems. It might be said that these few decades have replaced a near vacuum of information with a very large surplus. It is in the context of this flood of information that this series of mono­ graphs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assess­ ment of the state of the subject in a well-defined field.

Authors and Affiliations

  • Department of Biochemistry, University of Glasgow, Glasgow, UK

    Roger L. P. Adams

  • Department of Bioscience and Biotechnology, University of Strathclyde, Glasgow, UK

    Roy H. Burdon

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