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Bone Metastases

A translational and clinical approach

  • Book
  • © 2009

Overview

Editors:
  1. Dimitrios Kardamakis

    1. Dept. of Radiation Oncology, University of Patras Medical School, Patras, Greece

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  2. Vassilios Vassiliou

    1. Dept. of Radiation Oncology, University of Patras Medical School, Patras, Greece

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  3. Edward Chow

    1. Dept. of Radiation Oncology, University of Toronto Sunnybrook Health Sciences Centre, Toronto, Canada

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  • No similar edition in the market
  • Covers all aspects of metastatic bone disease
  • Contributors are expert in the concerned field
  • Concise information

Part of the book series: Cancer Metastasis - Biology and Treatment (CMBT, volume 12)

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About this book

Bone Metastases: A Translational and Clinical Approach serves as both an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume:

  • describes the molecular and cellular mechanisms involved in the formation of bone metastases,
  • comments on the role of angiogenesis,
  • presents the newer advances made in the understanding of the clinical picture and symptoms of patients,
  • analyses the role of bone markers in research and clinical practice
  • deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases.

This volume also covers the use of radiotherapy, surgery and systemic treatments for the management of metastatic bone disease and new therapeutic approaches. Moreover it may also serve as a guide for the clinical and therapeutic management of patients with metastatic bone disease.

Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for medical researchers, oncologists, orthopaedic surgeons and clinicians.

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Keywords

Table of contents (18 chapters)

  1. Front Matter

    Pages I-XVI
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  2. Fundamental Concepts of Bone Metastases

    1. Front Matter

      Pages 1-1
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    2. Bone Anatomy, Physiology and Function

      • Vassiliki Tzelepi, Athanassios C. Tsamandas, Vassiliki Zolota, Chrisoula D. Scopa
      Pages 3-30

    3. Pathophysiology of Bone Metastases

      • G. David. Roodman
      Pages 31-50

    4. Angiogenesis and Bone Metastasis: Implications for Diagnosis, Prevention and Treatment

      • Pelagia G. Tsoutsou, Michael I. Koukourakis
      Pages 51-76

    5. Natural History, Prognosis, Clinical Features and Complications of Metastatic Bone Disease

      • Vassilios Vassiliou, Edward Chow, Dimitrios Kardamakis
      Pages 77-92

    6. Bone Biomarkers in Research and Clinical Practice

      • Janet E. Brown, Edward Chow
      Pages 93-116

  3. Imaging Modalities

    1. Front Matter

      Pages 117-117
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    2. Radiologic Evaluation Of Skeletal Metastases: Role Of Plain Radiographs And Computed Tomography

      • Christina Kalogeropoulou, Anna Karachaliou, Peter Zampakis
      Pages 119-136

    3. The Contribution Of Nuclear Medicine In The Diagnosis Of Bone Metastases

      • Andor Glaudemans, Marnix Lam, Niels Veltman, Rudi Dierckx, Alberto Signore
      Pages 137-162

    4. Magnetic Resonance Imaging Of Metastatic Bone Disease

      • Ekaterini Solomou, Alexandra Kazantzi, Odysseas Romanos, Dimitrios Kardamakis
      Pages 163-181

  4. Therapeutic Strategies

    1. Front Matter

      Pages 183-183
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    2. Radiotherapy And Bone Metastases

      • Jan W.H. Leer, Yvette van der Linden
      Pages 185-193

    3. Biphosphonates In The Management Of Metastatic Bone Disease

      • Fred Saad, Arif Hussain
      Pages 195-231

    4. Combined Radiotherapy and Bisphosphonates: State of Art

      • Vassilios Vassiliou, Dimitrios Kardamakis
      Pages 233-250

    5. Biphosphonates in the Treatment of Bone Metastases – Osteonecrosis of the Jaw

      • Cesar Augusto Migliorati
      Pages 251-262

    6. Surgical Management of Bone Metastases

      • Markku Nousiainen, Cari Whyne, Albert Yee, Joel Finkelstein, Michael Ford
      Pages 263-286

    7. The Role of Chemotherapy in the Treatment of Bone Metastases

      • Thomas Makatsoris, Haralabos P. Kalofonos
      Pages 287-298

    8. Hormonotherapy of Bone Metastases

      • Konstantinos Kamposioras, Evangelos Briasoulis
      Pages 299-320

    9. Radionuclide Therapy

      • Giovanni Storto
      Pages 321-341
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Reviews

From the reviews:

“The aim of the book is to provide both an introduction and reference book on the field of metastatic bone disease. … Each chapter is extensively referenced. The book is very clear and comprehensive. … the book achieves its twin aims and is an extremely good reference book for those people researching and managing skeletal metastases. It will appeal to researchers, orthopaedic surgeons, oncologists and students … .” (Robert U. Ashford, European Journal of Orthopaedic Surgery & Traumatology, Vol. 21, 2011)

Editors and Affiliations

  • Dept. of Radiation Oncology, University of Patras Medical School, Patras, Greece

    Dimitrios Kardamakis, Vassilios Vassiliou

  • Dept. of Radiation Oncology, University of Toronto Sunnybrook Health Sciences Centre, Toronto, Canada

    Edward Chow

Bibliographic Information

  • Book Title: Bone Metastases

  • Book Subtitle: A translational and clinical approach

  • Editors: Dimitrios Kardamakis, Vassilios Vassiliou, Edward Chow

  • Series Title: Cancer Metastasis - Biology and Treatment

  • DOI: https://doi.org/10.1007/978-1-4020-9819-2

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2009

  • Hardcover ISBN: 978-1-4020-9818-5Published: 16 July 2009

  • eBook ISBN: 978-1-4020-9819-2Published: 21 July 2009

  • Series ISSN: 1568-2102

  • Series E-ISSN: 2215-1648

  • Edition Number: 1

  • Number of Pages: XVI, 400

  • Topics: Cancer Research, Oncology

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