PAS Proteins: Regulators and Sensors of Development and Physiology
Editors: Crews, Stephen T. (Ed.)
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- About this book
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PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.
Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders, and (6) mental health disorders such as social interactions and learning.
PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.
- Table of contents (10 chapters)
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Structure of the PAS Fold and Signal Transduction Mechanisms
Pages 1-16
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Signal Transduction in Prokaryotic PAS Domains
Pages 17-50
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bHLH-PAS Proteins in C. Elegans
Pages 51-68
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Drosophila bHLH-PAS Developmental Regulatory Proteins
Pages 69-108
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Methoprene-Tolerant, A PAS Gene Critical for Juvenile Hormone Signaling in Drosophila Melanogaster
Pages 109-132
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Table of contents (10 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- PAS Proteins: Regulators and Sensors of Development and Physiology
- Editors
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- Stephen T. Crews
- Copyright
- 2003
- Publisher
- Springer US
- Copyright Holder
- Kluwer Academic Publishers
- eBook ISBN
- 978-1-4615-0515-0
- DOI
- 10.1007/978-1-4615-0515-0
- Hardcover ISBN
- 978-1-4020-7586-5
- Softcover ISBN
- 978-1-4613-5115-3
- Edition Number
- 1
- Number of Pages
- XIII, 263
- Topics
