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  • © 2008

Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes

  • The first contributed volume to feature the recent developments which solely involve the pharmacological and biomaterials applications as well as the chemical properties of fullerenes

Part of the book series: Carbon Materials: Chemistry and Physics (CMCP, volume 1)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-viii
  2. Biomedical Applications of Functionalised Carbon Nanotubes

    • Alberto Bianco, Raquel Sainz, Shouping Li, Hélène Dumortier, Lara Lacerda, Kostas Kostarelos et al.
    Pages 23-50
  3. Antioxidant Properties of Water-Soluble Fullerene Derivatives

    • Florian Beuerle, Russell Lebovitz, Andreas Hirsch
    Pages 51-78
  4. Fullerenes as Photosensitizers in Photodynamic Therapy

    • Pawel Mroz, George P. Tegos, Hariprasad Gali, Timothy Wharton, Tadeusz Sarna, Michael R. Hamblin
    Pages 79-106
  5. Photodynamic Inactivation of Enveloped Viruses by Fullerene: Study of Efficacy and Safety

    • Vladimir V. Zarubaev, Inna Belousova, Vladimir Rylkov, Alexander Slita, Alexey Sirotkin, Pavel Anfimov et al.
    Pages 107-121
  6. Effects of Photoexcited Fullerene C60-Composites in Normal and Transformed Cells

    • S. V. Prylutska, I. I. Grynyuk, O. P. Matyshevska, A. A. Golub, A. P. Burlaka, Yu. I. Prylutskyy et al.
    Pages 123-137
  7. Biological Effects in Cell Cultures of Fullerene C60: Dependence on Aggregation State

    • Levon B. Piotrovsky, Mikhail Yu. Eropkin, Elena M. Eropkina, Marina A. Dumpis, Oleg I. Kiselev
    Pages 139-155
  8. Applications of Carbon-Based Nanomaterials for Drug Delivery in Oncology

    • Nicole H. Levi-Polyachenko, David L. Carroll, John H. Stewart IV
    Pages 223-266
  9. Pharmacological Applications of Biocompatible Carbon Nanotubes and Their Emerging Toxicology Issues

    • Tae-Joon Park, Jeffrey G. Martin, Robert J. Linhardt
    Pages 283-316
  10. Cellular Nanotubes: Membrane Channels for Intercellular Communication

    • Raquel Negrão Carvalho, Hans-Hermann Gerdes
    Pages 363-372
  11. Back Matter

    Pages 373-408

About this book

Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks.

Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances.

In addition, the funtionalization of nanotubes has not only produced relatively simple derivatives, but also complex hybrids with biological macromolecules, which show unique supramolecular architecture and which are promising in many medical applications.

The application of fullerenes and nanotubes in medicine is at the frontier of our knowledge, thus the work in this field represents the basis for future novel developments.

Editors and Affiliations

  • Lupi Chemical Research Institute, Rome, Italy

    Franco Cataldo

  • Dipartimento di Scienze Farmaceutiche, University of Trieste, Trieste, Italy

    Tatiana Ros

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access