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- About this book
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This book provides updated knowledge on the basic features and mechanisms of cellular aging established since its first manifestation at cellular level 40 years ago. Contributions of genetic and environmental factors, failure of genetic and cellular repair mechanisms, and the epigenetic modifications determine the final lifespan of cells. This book also provides an understanding on how aging mechanisms in mice, a most frequently used model, differ with that of humans who receive better tumor surveillance because of stringent controls on aging mechanisms. It also appraises the use of modern technology for aging studies and its intervention. This book serves as an excellent reading on cellular aging for undergraduate students, researchers and experts of this area.
- Table of contents (14 chapters)
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Aging Outside the Body: Usefulness of the Hayflick System
Pages 1-8
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Genetics of Cellular Aging
Pages 9-26
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Aging of Fibroblasts
Pages 27-46
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Aging of Endothelial Cells
Pages 47-65
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In Vitro Senescence of Human Osteoblasts
Pages 67-84
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Table of contents (14 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Aging of Cells in and Outside the Body
- Editors
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- S. Kaul
- Renu Wadwha
- Series Title
- Biology of Aging and its Modulation
- Series Volume
- 2
- Copyright
- 2003
- Publisher
- Springer Netherlands
- Copyright Holder
- Springer Science+Business Media Dordrecht
- eBook ISBN
- 978-94-017-0669-8
- DOI
- 10.1007/978-94-017-0669-8
- Hardcover ISBN
- 978-1-4020-1375-1
- Softcover ISBN
- 978-90-481-6314-4
- Edition Number
- 1
- Number of Pages
- IX, 276
- Number of Illustrations
- 38 b/w illustrations
- Topics
