Methods in Molecular Biology

Intrinsically Disordered Proteins

Methods and Protocols

Editors: Kragelund, Birthe B, Skriver, Karen (Eds.)

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook 209,00 €
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  • ISBN 978-1-0716-0524-0
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About this book

The edition details methods to study intrinsically disordered proteins (IDPs) including recent topics such as extremely high-affinity disordered complexes, kinetics that evade established concepts, liquid-liquid phase separation, and novel disorder-driven allosteric mechanisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Intrinsically Disordered Proteins: Methods and Protocols aims to help scientists with different backgrounds to further their investigations into these fascinating and dynamic molecules.

Chapter 24 is available open access under a CC BY 4.0 license via link.springer.com.

Table of contents (46 chapters)

Table of contents (46 chapters)
  • Disorder for Dummies: Functional Mutagenesis of Transient Helical Segments in Disordered Proteins

    Pages 3-20

    Daughdrill, Gary W.

  • Computational Prediction of Intrinsic Disorder in Protein Sequences with the disCoP Meta-predictor

    Pages 21-35

    Oldfield, Christopher J. (et al.)

  • Computational Prediction of Disordered Protein Motifs Using SLiMSuite

    Pages 37-72

    Edwards, Richard J. (et al.)

  • How to Annotate and Submit a Short Linear Motif to the Eukaryotic Linear Motif Resource

    Pages 73-102

    Gouw, Marc (et al.)

  • Analyzing the Sequences of Intrinsically Disordered Regions with CIDER and localCIDER

    Pages 103-126

    Ginell, Garrett M. (et al.)

Buy this book

eBook 209,00 €
price for Spain (gross)
  • ISBN 978-1-0716-0524-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover 259,99 €
price for Spain (gross)
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Bibliographic Information

Bibliographic Information
Book Title
Intrinsically Disordered Proteins
Book Subtitle
Methods and Protocols
Editors
  • Birthe B Kragelund
  • Karen Skriver
Series Title
Methods in Molecular Biology
Series Volume
2141
Copyright
2020
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-0716-0524-0
DOI
10.1007/978-1-0716-0524-0
Hardcover ISBN
978-1-0716-0523-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XVIII, 951
Number of Illustrations
39 b/w illustrations, 192 illustrations in colour
Topics