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Antiviral Methods and Protocols

  • Book
  • © 2000

Overview

Editors:
  1. Derek Kinchington

    1. St. Bartholomew’s and the Royal London School of Medicine and Dentristry,, London, UK

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    You can also search for this editor in PubMed   Google Scholar

  2. Raymond F. Schinazi

    1. Emory University, Decatur

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Methods in Molecular Medicine (MIMM, volume 24)

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Table of contents (30 protocols)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Changing Methods for Discovering Antiviral Drugs

    1. Changing Methods for Discovering Antiviral Drugs

      • Philip S. Jones
      Pages 1-12

  3. Laboratory Safety Considerations

    1. Laboratory Safety Considerations

      • Paul M. Feorino, John D. Williamson, Raymond F. Schinazi
      Pages 13-25

  4. Routine Quality Control Testing of Cell Cultures

    1. Routine Quality Control Testing of Cell Cultures

      • Alison Stacey, Glyn Stacey
      Pages 27-40

  5. Hepatitis Virus

    1. Front Matter

      Pages 41-41
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    2. Hep AD38 Assay

      • Robert W. King, Stephanie K. Ladner
      Pages 43-50

    3. Hepatitis B Virus Cell Culture Assays for Antiviral Activity

      • Karen Schmidt, Brent Korba
      Pages 51-67

    4. A Rapid Microtiter Assay for Duck Hepatitis Virus Reverse Transcriptase

      • Michael J. Otto, Richard A. Whitaker
      Pages 69-75

    5. Assays for Measuring Hepadnaviral Supercoiled DNA

      • Stephen A. Locamini, Gilda M. Civitico
      Pages 77-85

    6. Assays for Hepatitis B Virus DNA-and RNA-Dependent DNA Polymerase Activities

      • Timothy Shaw, Stephen A. Locarnini
      Pages 87-95

    7. Development of a Hepatitis C Virus RNA Helicase High Throughput Assay

      • Ann D. Kwong, Christine Risano
      Pages 97-116

  6. Herpesvirus

    1. Front Matter

      Pages 117-117
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    2. Determination of Viral Infectivity

      • David R. Harper
      Pages 119-127

    3. Antiviral Screening Assays for Human Herpesviruses 6 and 7

      • Jodi B. Black, Philip E. Pellett
      Pages 129-138

    4. Strategies for Evaluation of Antiviral Agents Against Epstein-Barr Virus in Culture

      • Jung-Chung Lin
      Pages 139-150

    5. Monitoring Drug Resistance for Herpesviruses

      • Graciela Andrei, Pierre Fiten, Erik De Clercq, Robert Snoeck, Ghislain Opdenakker
      Pages 151-169

    6. Herpesvirus Protease Assays

      • Peter Ertl, Linda Russell, Jane Angier
      Pages 171-182

  7. Human Immunodeficiency Virus

    1. Front Matter

      Pages 183-183
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    2. Testing Compounds for Antiviral Activity in Cell Cultures Infected with HIV

      • Donna Devine, Naomi Mathews, Derek Kinchington
      Pages 185-199

    3. Evaluation of Compounds That Prevent Reactivation of HIV-1 in OM-10.1 Cells

      • Salvatore T. Butera
      Pages 201-206
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Keywords

About this book

This latest addition to the Methods in Molecular Medicine series, Anti- ral Methods and Protocols, is opportune because there is an increasing int- est in discovering compounds that are effective against both chronic and acute viral infections. A number of the methods described in the volume are unp- lished and their inclusion indicates the speed at which this field is moving. This volume is not a review but each chapter contains methods validated by the experts who have spent time in developing the protocols. The hallmark of this series is the comprehensive way in which the me- ods are described, which includes a list of all the reagents needed for each protocol. Of importance is the section on tips and pitfalls that the authors have discovered while developing their protocols. The manual itself is designed to be used by researchers in universities and industry who are familiar with a range of biological techniques but who want to set up quickly a novel assay system. We encourage a dialog between readers and authors, which may also result in useful collaborations.

Reviews

"...will be of great benefit to all involved with antiviral development..." -Antiviral Research

"...Together with some useful general discussions on safety and new approaches to antiviral research this volume offers extremely useful information for both the pharmaceutical industry and the academic researcher."-Microbiology Today

"...the editors are to be congratulated for assembling an impressive array of experts in the field as authors for the chapters and the book should remain a valuable reference work for many years, despite the rapidly moving nature of the discipline." - Journal of Antimicrobial Chemotherapy

Editors and Affiliations

  • St. Bartholomew’s and the Royal London School of Medicine and Dentristry,, London, UK

    Derek Kinchington

  • Emory University, Decatur

    Raymond F. Schinazi

Bibliographic Information

  • Book Title: Antiviral Methods and Protocols

  • Editors: Derek Kinchington, Raymond F. Schinazi

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592592457

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2000

  • Hardcover ISBN: 978-0-89603-561-4Published: 14 September 1999

  • Softcover ISBN: 978-1-61737-073-1Published: 08 October 2011

  • eBook ISBN: 978-1-59259-245-6Published: 01 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XIV, 404

  • Topics: Infectious Diseases

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