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Inositol and Phosphoinositides

Metabolism and Regulation

  • Book
  • © 1985

Overview

Editors:
  1. John E. Bleasdale

    1. Department of Biochemistry, University of Texas Health Science Center, Dallas, USA

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  2. Joseph Eichberg

    1. Department of Biochemical and Biophysical Sciences, University of Houston, Houston, USA

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  3. George Hauser

    1. Ralph Lowell Laboratories, McLean Hospital, Harvard Medical School, Belmont, USA

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Part of the book series: Experimental Biology and Medicine (EBAM, volume 6)

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Table of contents (41 chapters)

  1. Front Matter

    Pages i-xxii
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  2. Myo-Inositol Metabolism and Homeostasis

    1. Front Matter

      Pages 1-1
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  3. Myo-Inositol Metabolism and Homeostasis

    1. The Mechanism of Enzymatic Isomerization of Glucose 6-Phosphate to L-Myo-Inositol 1-phosphate

      • F. Eisenberg Jr., T. Maeda
      Pages 3-11

    2. Regulation of the Lipid Composition of Lung Surfactant

      • John E. Bleasdale
      Pages 13-30

    3. Nutritional Regulation of the Composition, Metabolism, and Function of Cellular Phosphatidylinositol

      • Bruce J. Holub
      Pages 31-47

    4. Detection of Receptor-Linked Phosphoinositide Metabolism in Brain of Lithium-Treated Rats

      • William R. Sherman, Michael P. Honchar, Ling Y. Munsell
      Pages 49-65

    5. Propranolol-Induced Membrane Perturbation and the Metabolism of Phosphoinositides and Arachidonoyl Diacylglycerols in the Retina

      • Nicolas G. Bazan, Ana M. Roccamo de Fernandez, Norma M. Giusto, Monica G. Ilincheta de Boschero
      Pages 67-82

    6. Neurotransmitter Receptor-Mediated Myo-Inositol 1-Phosphate Accumulation in Hippocampal Slices

      • Aaron Janowsky, Rodrigo Labarca, Steven M. Paul
      Pages 83-90

    7. Early Events in the Selective Cytotoxicity to Tumor Cells Induced by Liposomes Containing Plant Phosphatidylinositol

      • Marti Jett, Carl R. Alving
      Pages 91-97

  4. Back Matter

    Pages 99-104
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  5. Phosphoinositide Biosynthesis and Degradation

    1. Front Matter

      Pages 105-105
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    2. Phosphatidylinositol Synthase in Mammalian Pancreas

      • Mabel Hokin-Neaverson, Gregory S. Parries
      Pages 107-121

    3. The Enzymology of Phosphoinositide Catabolism, with Particular Reference to Phosphatidyl-Inositol 4,5-Bisphosphate Phosphodiesterase

      • R. F. Irvine, A. J. Letcher, D. J. Lander, R. M. C. Dawson
      Pages 123-135

    4. Subcellular Sites of Polyphosphoinositide Metabolism in Rat Liver

      • M. A. Seyfred, C. D. Smith, L. E. Farrell, W. W. Wells
      Pages 137-159

    5. Loss of Phosphatidylinositol and Gain in Phosphatidate in Neutrophils Stimulated with Fmet-Leu-Phe

      • S. Cockcroft, D. Allan
      Pages 161-177

    6. The De Novo Phospholipid Synthesis Effect: Occurrence, Characteristics, Underlying Mechanisms and Functional Significance in Hormone Action and Secretion

      • Robert V. Farese
      Pages 179-198

    7. Hydrolysis of Phosphatidylinositol 4-phosphate and Phosphatidylinositol(4,5)-Bisphosphate by Specific Phosphomonoesterases in Human Erythrocytes

      • F. B. St. C. Palmer, S. E. Mack
      Pages 199-206

    8. Drug-Induced Modifications of Phosphoinositide Metabolism

      • P. Marche, A. Girard, S. Koutouzov
      Pages 207-212

  6. Back Matter

    Pages 213-218
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  7. Receptor-Mediated Alterations in Phosphoinositide Metabolism

    1. Front Matter

      Pages 219-219
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Keywords

About this book

The Chilton Conference on Inositol and Phosphoinositides, held on January 9-11, 1984 at Southwestern Medical School, University of Texas Health Science Center, Dallas, Texas, was the third in a series of conferences on cyclitols and phosphoinositides. The first took place in 1968 in New York [Ann. New York Acad. Sci. (1969), 765,508-819] and the second was held in 1977 in East Lansing, Michigan [eyclitols and Phosphoinositides, Wells, W. W. and Eisenberg, F. , eds. , (1978) Academic press, New York, pp. 1-607. ] In the interim since the previous conference, not only has the pace of research in the field accelerated markedly, but the physiological importance of phosphoinositide metabolism has become apparent to an increasing number of investigators from diverse fields in the life sciences. Thus it seemed to us timely for both recent and established workers in this area, as well as others whose interests impinged on it, to meet in order to disseminate new information, to review, and perhaps arrive at, a consensus of our current understanding of the role of inositol and phosphoinositides, and to establish new directions for research for the next few years. The expansion of the field since the last meeting made it mandatory to restrict the scope of the topics covered at the conference, primarily to aspects dealing with mammalian systems. We sincerely regretted the exclusion of recent research on cyclitols and phosphoinositides in microbes and plants and hope that these areas will be included in future conferences.

Editors and Affiliations

  • Department of Biochemistry, University of Texas Health Science Center, Dallas, USA

    John E. Bleasdale

  • Department of Biochemical and Biophysical Sciences, University of Houston, Houston, USA

    Joseph Eichberg

  • Ralph Lowell Laboratories, McLean Hospital, Harvard Medical School, Belmont, USA

    George Hauser

Bibliographic Information

  • Book Title: Inositol and Phosphoinositides

  • Book Subtitle: Metabolism and Regulation

  • Editors: John E. Bleasdale, Joseph Eichberg, George Hauser

  • Series Title: Experimental Biology and Medicine

  • DOI: https://doi.org/10.1007/978-1-4612-5184-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Humana Press Inc. 1985

  • Hardcover ISBN: 978-0-89603-074-9Published: 20 May 1985

  • Softcover ISBN: 978-1-4612-9602-7Published: 05 October 2011

  • eBook ISBN: 978-1-4612-5184-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXII, 698

  • Topics: Biochemistry, general

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