Comparative Genomics

1. Front Matter

   Pages i-xiii

   PDF

2. Introduction

   1. Front Matter

      Pages 1-1

      PDF

   2. Comparative Genomics

      • David Sankoff, Joseph H. Nadeau

      Pages 3-7

3. Mechanisms

   1. Front Matter

      Pages 9-9

      PDF

   2. Cytogenetics, Molecular Genetics, Population Genetics

      • David Sankoff, Joseph H. Nadeau

      Pages 11-12

   3. Benefits of a Model of Segregation for the Understanding of Chromosomal Evolution

      • Thomas Faraut, Jacques Demongeot

      Pages 13-18

   4. Fixation of Chromosomal Rerrangements

      • Bryant F. McAllister

      Pages 19-27

   5. The Pathological Consequences and Evolutionary Implications of Recent Human Genomic Duplications

      • Christine O’Keefe, Evan Eichler

      Pages 29-46

   6. High Frequency of Inversions During Eukaryote Gene Order Evolution

      • Aoife McLysaght, Cathal Seoighe, Kenneth H. Wolfe

      Pages 47-58

   7. Human and Mouse DNA Sequence Comparisons: Further Evidence for a Mosaic Model of Genomic Evolution

      • Gord Brown, Duane Martindale, Michael D. Wilson, Ben F. Koop

      Pages 59-69

   8. Hot Spots in Chromosomal Breakage: From Description TC Etiology

      • Jacques Demongeot, Juglio Aracena, Samia Ben Lamine, Marie-Ange Mermet, Olivier Cohen

      Pages 71-83

4. Organelles: Mitochondria and Chloroplats

   1. Front Matter

      Pages 85-85

      PDF

   2. Rearrangements in Small Genomes

      • David Sankoff, Joseph H. Nadeau

      Pages 87-88

   3. Chloroplast Gene Order and the Divergence of Plants and Algae, from the Normalized Number of Induced Breakpoints

      • David Sankoff, Mélanie Deneault, David Bryant, Claude Lemieux, Monique Turmel

      Pages 89-98

   4. An Empirical Comparison of Phylogenetic Methods on Chloroplast Gene Order Data in Campanulaceae

      • Mary E. Cosner, Robert K. Jansen, Bernard M. E. Moret, Linda A. Raubeson, Li-San Wang, Tandy Warnow et al.

      Pages 99-121

   5. Gene Order and Phylogenetic Information

      • Cyril Gallut, Véronique Barriel, Régine Vignes

      Pages 123-132

   6. The Duplication/Random Loss Model for Gene Rearrangement Exemplified by Mitochondrial Genomes of Deuterostome Animals

      • Jeffrey L. Boore

      Pages 133-147

   7. MAPIT—a Semi-Automated Approach to the Representation of Genetic Maps

      • Alexander Nip, Lin Liu, Charbel Seif, B. Franz Lang, Gertraud Burger

      Pages 149-161

5. Combinatorial Algorithms

   1. Front Matter

      Pages 163-163

      PDF

   2. A New Set of Problems for a New Kind of Data

      • David Sankoff, Joseph H. Nadeau

      Pages 165-170

A comprehensive account of genomic rearrangement, focusing on the mechanisms of inversion, translocation, gene and genome duplication and gene transfer and on the patterns that result from them in comparative maps. Includes analyses of genomic sequences in organelles, prokaryotes and eukaryotes as well as comparative maps of the nuclear genomes in higher plants and animals. The book showcases a variety of algorithmic and statistical approaches to rearrangement and map data.

• Organelle
• gene transfer
• genes
• genetics
• prokaryotes

• Université de Montréal, Canada

  David Sankoff

• Case Western Reserve University, USA

  Joseph H. Nadeau

Policies and ethics