Textbook of Pulmonary Vascular Disease

1. Front Matter

   Pages i-xxxii

   PDF

2. Structure, Function and Regulation

   1. Front Matter

      Pages 1-1

      PDF

3. STRUCTURE, FUNCTION AND REGULATION

   1. The Human Pulmonary Circulation: Historical Introduction

      • John B. West

      Pages 3-12

   2. Microcirculation of the Lung: Functional and Anatomic Aspects

      • Joan Gil

      Pages 13-24

   3. Pulmonary Vascular Development

      • Rosemary C. Jones, Diane E. Capen

      Pages 25-60

   4. Pulmonary Vascular Function

      • Robert Naeije, Nico Westerhof

      Pages 61-72

   5. Pulmonary Vascular Mechanics

      • Alejandro Roldán-Alzate, Naomi C. Chesler

      Pages 73-89

   6. Modeling of the Pulmonary Vasculature

      • Merryn H. Tawhai, Kelly S. Burrowes

      Pages 91-103

   7. Metabolic and Clearance Function at the Pulmonary Microvascular Endothelial Surface in Pulmonary Hypertension

      • Stylianos E. Orfanos, David Langleben

      Pages 105-115

   8. The Influence of the Major Vasoactive Mediators Relevant to the Pathogenesis of Pulmonary Hypertension

      • Margaret R. MacLean, Yvonne Dempsie

      Pages 117-133

   9. The Normal Fetal and Neonatal Pulmonary Circulation

      • Steven H. Abman, Robin H. Steinhorn

      Pages 135-146

   10. Excitation–Contraction Coupling and Regulation of Pulmonary Vascular Contractility

       • Jeremy P. T. Ward, Greg A. Knock

       Pages 147-165

   11. Endothelial Regulation of Pulmonary Vascular Tone

       • Stephen Y. Chan, Joseph Loscalzo

       Pages 167-195

   12. Acute Lung Injury: The Injured Lung Endothelium, Therapeutic Strategies for Barrier Protection, and Vascular Biomarkers

       • Eddie T. Chiang, Ting Wang, Joe G. N. Garcia

       Pages 197-222

   13. Ion Channels and Transporters in the Pulmonary Vasculature: A Focus on Smooth Muscle

       • Amy L. Firth, Jason X.-J. Yuan

       Pages 223-244

   14. Receptor-Mediated Signal Transduction and Cell Signaling

       • Fiona Murray, Jason X.-J. Yuan, Paul A. Insel

       Pages 245-260

   15. Role of Calcium as a Second Messenger in Signaling: A Focus on Endothelium

       • Donna L. Cioffi, Christina J. Barry, Troy Stevens

       Pages 261-272

   16. Caveolae and Signaling in Pulmonary Vascular Endothelial and Smooth Muscle Cells

       • Geerten P. van Nieuw Amerongen, Richard D. Minshall, Asrar B. Malik

       Pages 273-285

   17. The Chemistry of Biological Gases

       • D. Jeannean Carver, Lisa A. Palmer

       Pages 287-299

   18. Role of Oxygen-Derived Species in the Regulation of Pulmonary Vascular Tone

       • Michael S. Wolin, Mansoor Ahmad, Sachin A. Gupte

       Pages 301-311

Textbook of Pulmonary Vascular Diseases combines basic scientific knowledge on the pulmonary circulatory system at levels of the molecule, cell, tissue, and organ with clinical diagnosis and treatment of pulmonary vascular diseases. State-of-the-art techniques and their potential applications in research, diagnosis, and treatment of pulmonary vascular diseases are also covered.

From the reviews:

“The book begins by detailing the known elements of structure and physiology, then outlines several research tools commonly used in the investigation of pulmonary vasculature before covering mechanisms of pulmonary vascular injury, disease states, and available treatment. … The intended audience centers on clinicians, but physician scientists, principal investigators, and others with an interest in pulmonary vascular research also can use it as a reference. … This is a unique book and has no comparison. … I will refer to this text regularly.” (Warren Bradley Fields, Doody’s Review Service, August, 2011)

• Departments of Medicine, COMRB Rm. 3131 (MC 719), University of Illinois at Chicago, Chicago, USA

  Jason X. -J. Yuan

• 310 Admin.Office Building (MC 672), University of Illinois at Chicago, Chicago, USA

  Joe G.N. Garcia

• Department of Medicine, University of California, San Diego, La Jolla, USA

  John B. West

• Dept. Pulmonary & Critical Care Medicine, Massachusetts General Hospital, Boston, USA

  Charles A. Hales

• Department of Medicine, University of Chicago Medical Center, Chicago, USA

  Stuart Rich

• Department of Medicine, University of Chicago School of Medicine, Chicago, USA

  Stephen L. Archer

Jason X.-J. Yuan, MD, PhD is Professor of Medicine, University of Illinois at Chicago, Chicago, IL Joe G.N. Garcia, MD is Earl Banes Professor of Medicine and Vice Chancellor for Research, University of Illinois at Chicago, Chicago, IL Charles A. Hales, MD is Professor of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA Stuart Rich, MD is Professor of Medicine, University of Chicago, Chicago, IL Stephen L. Archer, MD is Harold Hines Jr. Professor of Medicine and Chief of Cardiology, University of Chicago, Chicago, IL John B. West, MD, PhD, DSc is Distinguished Professor of Physiology and Medicine, University of California, San Diego, La Jolla, CA

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