Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3
Basic Science and Clinical Relevance Part B
Editors: Sullivan, D.A., Stern, M.E., Tsubota, K., Dartt, D.A., Sullivan, R.M., Bromberg, B.B. (Eds.)
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During the past several decades, a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays a critical role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in numerous individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perforation of the cornea, an increased incidence of infectious disease, and potentionally pronounced visual disability and blindness.
- Table of contents (196 chapters)
-
-
Understanding Dry Eye Syndrome
Pages 3-16
Tsubota, Kazuo
-
GDNF Family Signalling in Exocrine Tissues: Distinct Roles for GDNF and Neurturin in Parasympathetic Neuron Development
Pages 19-26
Rossi, Jari (et al.)
-
The Influence of Aging in the Insulin-Signaling System in Rat Exocrine Glands
Pages 27-31
Rocha, Eduardo M. (et al.)
-
Cloning, Partial Sequencing and Expression of Rabbit Lacrimal Gland β-Hexosaminidase
Pages 33-39
Gierow, J. Peter (et al.)
-
Differential Expression of Adenylyl Cyclase mRNAs in Lacrimal Glands of NZB/NZW and NOD Pre-Autoimmune Mice
Pages 41-49
Meneray, Michele A. (et al.)
-
M3 Receptor Autoimmunity: Losing Tolerance to a Familiar Protein
Pages 51-58
Mircheff, Austin K. (et al.)
-
Presence of α-and β-Integrin Subunits in Rabbit Lacrimal Gland Acinar Cells Cultured on a Laminin-Rich Matrix
Pages 59-63
Gierow, J. Peter (et al.)
-
The Effects of Sensory and Parasympathetic Denervation on the Kinases and Initiation Factors Controlling Protein Synthesis in the Lacrimal Gland
Pages 65-70
Nguyen, Doan H. (et al.)
-
Familial Dysautonomia in Review: Diagnosis and Treatment of Ocular Manifestations
Pages 71-80
Josaitis, Cathleen A. (et al.)
-
Somatostatin-Like Immunoreactivity (SLIR) in Rat Harderian and Meibomian Glands and Glands of Zeis
Pages 81-89
Lorber, Mortimer
-
Neuronal Nitric Oxide Synthase is Expressed in the Mouse Lacrimal Gland and Neurons of Pterygopalatine Ganglion
Pages 91-95
Ding, Chuanqing (et al.)
-
Effects of Ageing on Secretagogue-Evoked Protein Output, Peroxidase Secretion and Protein Synthesis in the Isolated Rat Lacrimal Gland
Pages 97-101
Singh, Jaipaul (et al.)
-
Effects of Ageing on Changes in Morphology of the Rat Lacrimal Gland
Pages 103-107
Adeghate, Ernest (et al.)
-
The Role of Gap Junctions in Lacrimal Acinar Cells: The Formation of Tears
Pages 109-113
Brink, Peter R. (et al.)
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Lipase mRNAs Expressed in Lacrimal and Harderian Glands
Pages 115-119
Remington, Susann G. (et al.)
-
Gender-Related Differences in Gene Expression of the Lacrimal Gland
Pages 121-127
Richards, S. M. (et al.)
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Identification of Androgen-Regulated Genes in the Lacrimal Gland
Pages 129-135
Liu, M. (et al.)
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Identification of Androgen Receptors in Rabbit Lacrimal Gland by Immunohistochemsitry
Pages 137-141
Aupperlee, Mark D. (et al.)
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Androgen Influence on Lymphocyte Gene Expression
Pages 143-151
Bijlsma, W. R. (et al.)
-
Potential Role of Disrupted Lacrimal Acinar Cells in Dry Eye during Pregnancy
Pages 153-157
Schechter, Joel E. (et al.)
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A New Model System for Studying Lacrimal Physiology Using Cultured Lacrimal Gland Acinar Cells on Matrigel® Rafts
Pages 159-163
Stevenson, Douglas (et al.)
-
Genetic Separation of the Human Lacritin Gene (“LACRT”) and Triple A (Allgrove) Syndrome on 12Q13
Pages 167-174
Kumar, Rajesh (et al.)
-
Ca2+ Signaling in Polarized Exocrine Cells
Pages 175-183
Kiselyov, Kirill (et al.)
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Role of Ca2+ and Protein Kinase C in Cholinergic, and α1-Adrenergic Agonists and EGF Stimulated Mitogen-Activated Protein Kinase Activity in Lacrimal Gland
Pages 185-190
Ríos, José D. (et al.)
-
A Model of Fluid Secretion by the Acinar Cells of the Mouse Lacrimal Gland
Pages 191-197
Walcott, Benjamin (et al.)
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Cytoskeletal Participation in Stimulated Secretion and Compensatory Apical Plasma Membrane Retrieval in Lacrimal Gland Acinar Cells
Pages 199-205
Costa, Silvia R. (et al.)
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Glycolipid-Rich Membrane Microdomains in Lacrimal Acinar Cell Endomembrane Compartments
Pages 207-211
Qian, Limin (et al.)
-
Epidermal Growth Factor Traffic in Lacrimal Acinar Cells
Pages 213-217
Xie, Jiansong (et al.)
-
Immunolocalization and Physiological Effect of Serotonin in the Porcine Lacrimal Gland
Pages 219-223
Adeghate, Ernest (et al.)
-
Effects of Preganglionic Parasympathetic Denervation on the Rabbit Lacrimation
Pages 225-229
Toshida, Hiroshi (et al.)
-
Prolactin Inhibits Carbachol-Dependent Secretion by Lacrimal Acinar Cells in Vitro
Pages 231-235
Casbon, Amy J. (et al.)
-
Effect of Overexpression of Protein Kinase Cα on Rat Lacrimal Gland Protein Secretion
Pages 237-241
Hodges, Robin R. (et al.)
-
Epidermal Growth Factor Stimulates Fluid Transport in SV40 Transformed Rabbit Lacrimal Gland Cells
Pages 243-247
Iserovich, Pavel (et al.)
-
Nucleoside and Nucleotide Stimulation of Fluid Secretion in the Pigmented Rabbit Conjunctiva
Pages 249-254
Lee, Vincent H. L. (et al.)
-
Metabolism and Transport of Purinergic Receptor Agonists in Rabbit Conjunctival Epithelial Cells
Pages 255-259
Gukasyan, Hovhannes J. (et al.)
-
Potency and Duration of Action of Synthetic P2Y2 Receptor Agonists on Schirmer Scores in Rabbits
Pages 261-265
Yerxa, Benjamin R. (et al.)
-
Mechanism by Which Bacterial Flagellin Stimulates Host Mucin Production
Pages 269-273
McNamara, Nancy (et al.)
-
Mucins and Ocular Surface Disease
Pages 275-281
Hibino, Sawako H. (et al.)
-
Functional Processing of Ocular Mucins
Pages 283-288
Berry, Monica (et al.)
-
ErbB2 and Its Ligand Muc4 (Sialomucin Complex) in Rat Lacrimal Gland
Pages 289-295
Carraway, Kermit L. (et al.)
-
Role of Mitogen-Activated Protein Kinase in Cholinergic Stimulation of Conjunctival Goblet Cell Secretion
Pages 297-300
Dartt, Darlene A. (et al.)
-
Isolation and Characterization of Human Goblet Cells in Vitro: Regulation of Proliferation and Activation of Mitogen-Activated Protein Kinase by EGF and Carbachol
Pages 301-305
Shatos, Marie A. (et al.)
-
Human Conjunctival Epithelium in Culture: A Tool to Assay New Therapeutic Strategies for Dry Eye
Pages 307-311
Diebold, Yolanda (et al.)
-
Ocular TFF-Peptides: New Mucus-Associated Secretory Products of Conjunctival Goblet Cells
Pages 313-316
Langer, Gesa (et al.)
-
Topically Applied 15-(S)-HETE Stimulates Mucin Production by Corneal Epithelium
Pages 317-321
Ubels, John L. (et al.)
-
Effects of 15(S)-HETE on Human Conjunctival Mucin Secretion
Pages 323-327
Jumblatt, James E. (et al.)
-
Evaluation of the Effects of 15(S)-HETE on Corneal Epithelial Cells: An Electrophysiological and Cytochemical Study
Pages 329-333
Azar, Ramzy G. (et al.)
-
Preservation of Corneal Integrity by the Mucin Secretagogue 15(S)-HETE in a Rabbit Model of Desiccation-Induced Dry Eye
Pages 335-340
Gamache, Daniel A. (et al.)
-
Purification and Chemical Characterization of the High Molecular Weight Glycoconjugate Fraction of the Bovine Tear Film and Comparison to Mucins from Other Sources
Pages 341-345
Ball, Malcolm S. (et al.)
-
Sialic Acid in Normal and Dry Eye Tear Fluid
Pages 347-351
Nakamura, Yo (et al.)
-
Gefarnate Stimulates Goblet Cell Repopulation Following an Experimental Wound to the Tarsal Conjunctiva in the Dry Eye Rabbit
Pages 353-357
Toshida, Hiroshi (et al.)
-
Mucin Ophthalmic Solution Treatment of Dry Eye
Pages 359-362
Shigemitsu, Toshiro (et al.)
-
The Lacunar Sulci: A New Test to Measure the Shrinkage of Ocular Surface, and Its Relation with the Number of Goblet Cells
Pages 363-369
Murube, Juan (et al.)
-
Meibomian Gland and Tear Film Lipids: Structure, Function and Control
Pages 373-378
McCulley, James P. (et al.)
-
Androgen Regulation of Lipogenesis
Pages 379-387
Swinnen, Johannes V. (et al.)
-
Sex Steroids, the Meibomian Gland and Evaporative Dry Eye
Pages 389-399
Sullivan, D. A. (et al.)
-
The Lipid Layer and Stability of Tears in Human Newborns
Pages 401-404
Isenberg, Sherwin J. (et al.)
-
Interface Properties of Simplified Tear-Like Fluids in Relation to Lipid and Aqueous Layers Composition
Pages 405-417
Miano, Fausto (et al.)
-
Effect of an Oil and Water Emulsion on Tear Evaporation Rate
Pages 419-423
Pearce, E. Ian (et al.)
-
Evaporation from the Human Tear Film Studied by Interferometry
Pages 425-429
King-Smith, P. Ewen (et al.)
-
The Effects of Dietary and Pharmacological Manipulation on Lipid Production in the Meibomian and Harderian Glands of the Rabbit
Pages 431-440
Millar, Thomas J. (et al.)
-
Correlations between Nutrient Intake and the Polar Lipid Profiles of Meibomian Gland Secretions in Women with Sjögren’s Syndrome
Pages 441-447
Sullivan, B. D. (et al.)
-
Impact of Androgen Deficiency on the Lipid Profiles in Human Meibomian Gland Secretions
Pages 449-458
Sullivan, B. D. (et al.)
-
Gender-Associated Differences in Gene Expression of the Meibomian Gland
Pages 459-463
Yamagami, H. (et al.)
-
Androgen Control of Gene Expression in the Rabbit Meibomian Gland
Pages 465-476
Steagall, R. J. (et al.)
-
Androgen Influence on Gene Expression in the Meibomian Gland
Pages 477-481
Yamagami, H. (et al.)
-
Estrogen and Progesterone Effects on the Morphology of the Mouse Meibomian Gland
Pages 483-488
Suzuki, T. (et al.)
-
Gene Expression and Fat Deposit in Primary Cultures of Rat Meibomian Gland Cells
Pages 489-493
Sumida, Michihiro (et al.)
-
The Effects of Anionic and Zwitterionic Phospholipids on the Tear Film Lipid Layer
Pages 495-499
Korb, Donald R. (et al.)
-
Alleviation of Computer-Induced Eye Discomfort Syndrome and Associated Lipid Layer Changes
Pages 501-506
Korb, Donald R.
-
Effects of Fluorescein Instillation Methods on the Tear Film Lipid Layer
Pages 507-512
Greiner, Jack V. (et al.)
-
Blinking Frequency and the Thickness of the Lipid Layer
Pages 513-516
Berke, Andreas
-
Assessment of Meibomian Gland Function by a Newly-Developed Laser Meibometer
Pages 517-520
Komuro, Aoi (et al.)
-
The Tear Film and Defense Against Infection
Pages 523-530
Fleiszig, Suzanne M. J. (et al.)
-
Nerve Growth Factor (NGF): An Important Molecule for Trophism and Healing of the Ocular Surface
Pages 531-537
Bonini, Stefano (et al.)
-
Changes in the Diurnal Pattern of the Distribution of Gelatinases and Associated Proteins in Normal and Pathological Tear Fluids: Evidence that the PMN Cell is a Major Source of MMP Activity in Tear Fluid
Pages 539-545
Sack, Robert A. (et al.)
-
Protection of Human Efferent Tear Ducts by Antimicrobial Peptides
Pages 547-553
Paulsen, Friedrich P. (et al.)
-
Tear Lipocalin: Structure, Function and Molecular Mechanisms of Action
Pages 555-565
Glasgow, Ben J. (et al.)
-
Vitamin E Associated with the Lipocalin Fraction of Human Tears
Pages 567-572
Glasgow, Ben J. (et al.)
-
Characterization of a Lipophilin in Rabbit Tears
Pages 573-580
Glasgow, Ben J. (et al.)
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The Role of Lipocalin in Determining the Physical Properties of Tears
Pages 581-585
Tiffany, John M. (et al.)
-
Age-Related Changes in Human Tear Composition and Stability
Pages 587-591
Tiffany, John M. (et al.)
-
Dynamic Surface Activity of Biological Fluids, Ophthalmic Solutions and Nanostructures
Pages 593-599
Tonge, Steve (et al.)
-
Mass Spectrometric Techniques Applied to the Analysis of Human Tears: A Focus on the Peptide and Protein Constituents
Pages 601-605
Fung, Kim (et al.)
-
Insulin, Insulin Receptor and Insulin-Like Growth Factor-I Receptor on the Human Ocular Surface
Pages 607-610
Rocha, Eduardo M. (et al.)
-
Immunodacryochemistry (Immunoferning): A New Screening Method for Proteins in Tears
Pages 611-615
Setten, Gysbert
-
Different Concentrations of Amino Acids in Tears of Normal and Human Dry Eyes
Pages 617-621
ChenZhuo, Lucia (et al.)
-
Changes in the Tear Protein Patterns of Diabetic Patients Using Two-Dimensional Electrophoresis
Pages 623-626
Herber, Simone (et al.)
-
Enzymatic Mechanisms in Corneal Ulceration with Specific Reference to Familial Dysautonomia: Potential for Genetic Approaches
Pages 629-639
Fini, M. Elizabeth (et al.)
-
Pathological Keratinization of Ocular Surface Epithelium
Pages 641-646
Kinoshita, Shigeru (et al.)
-
Experimentally Induced Dry Eye Produces Ocular Surface Inflammation and Epithelial Disease
Pages 647-655
Dursun, Dilek (et al.)
-
In Vivo Confocal Microscopy for Studying Corneal Diseases and Conditions Associated with Corneal Nerve Damage
Pages 657-665
Tervo, Timo M. (et al.)
-
Ocular Surface Changes in Type 1 Diabetic Patients
Pages 667-672
Aragona, Pasquale (et al.)
-
Serum- and Serum Deprivation-Induced Transcriptional Profiles of Cultured Conjunctival Epithelial Cells
Pages 673-676
Higuchi, Akihiro (et al.)
-
Shear-Induced ATP Release by Cultured Rabbit Corneal Epithelial Cells
Pages 677-685
Srinivas, S. P. (et al.)
-
The Role of Nitric Oxide in Ocular Surface Diseases
Pages 687-695
Kim, J. C. (et al.)
-
Relationship between in Vitro Toxicity of Benzalkonium Chloride (BAC) and Preservative-Induced Dry Eye
Pages 697-702
Saint Jean, M. (et al.)
-
Corneal Epithelial Permeability and Dry Eye Treatment
Pages 703-706
Benitez-del-Castillo, Jose M. (et al.)
-
Observation of Tear Film in Recurrent Corneal Erosion and Epithelial Basement Membrane Dystrophy
Pages 707-710
Sugita, Jiro (et al.)
-
The Effect of Tear Film and Ocular Surface Management on Myopic Lasik Outcomes
Pages 711-717
Albietz, Julie (et al.)
-
A Comparison of Corneal and Conjunctival Sensitivity to a Thermally Cooling Stimulus
Pages 719-722
Murphy, Paul J. (et al.)
-
The Effect of Acupuncture on the Temperature of the Ocular Surface in Conjunctivitis Sicca Measured by Non-Contact Thermography: Preliminary Results
Pages 723-726
Nepp, Johannes (et al.)
-
Role of Immunity and Inflammation in Corneal and Ocular Surface Disease Associated with Dry Eye
Pages 729-738
Dana, M. Reza (et al.)
-
Dry eye and Delayed Tear Clearance: “A Call to Arms”
Pages 739-743
Pflugfelder, Stephen C. (et al.)
-
Innate Immunity in the Cornea: A Putative Role for Keratocytes in the Chemokine Response to Viral Infection of the Human Corneal Stroma
Pages 745-751
Natarajan, Kanchana (et al.)
-
The Role of ICAM-1 as a Signal Protein for Predisposition of Ocular Surface Inflammation
Pages 753-759
Stern, Michael E. (et al.)
-
Flow Cytometric Analysis of the Inflammatory Marker HLA DR in Dry Eye Syndrome: Results from 12 Months of Randomized Treatment with Topical Cyclosporin A
Pages 761-769
Baudouin, Christophe (et al.)
-
Pathogenesis of Autoimmune Lacrimal Gland Disease in MRL/MPJ Mice
Pages 771-776
Jabs, Douglas A. (et al.)
-
ICAM-1: Its Role in the Pathophysiology of Immune Activation in the MRL/LPR Mouse
Pages 777-781
Gao, Jianping (et al.)
-
Proinflammatory Cytokine Inhibition of Lacrimal Gland Secretion
Pages 783-787
Kublin, Claire Larkin (et al.)
-
Effect of Anti-Inflammatory Cytokines on the Activation of Lymphocytes by Lacrimal Gland Acinar Cells in an Autologous Mixed Cell Reaction
Pages 789-794
Trousdale, Melvin D. (et al.)
-
IL-2 Immunoreactive Proteins in Lacrimal Acinar Cells
Pages 795-799
Zhang, Yan (et al.)
-
Immunopathogenesis of Conjunctival Histopathologic Alteration in Non-Sjögren’s Keratoconjunctivitis Sicca
Pages 801-803
Ye, Hongqing Q. (et al.)
-
Topical Cyclosporine a (2%) Eyedrops in the Therapy of Atopic Keratoconjunctivitis and Keratoconjunctivitis Vernalis
Pages 805-812
Tomida, I. (et al.)
-
Apoptosis: The Eyes Have It
Pages 815-820
Elzey, Bennett D. (et al.)
-
Apoptosis in the Cornea in Response to Epithelial Injury: Significance to Wound Healing and Dry Eye
Pages 821-826
Wilson, Steven E. (et al.)
-
Mechanisms of Apoptosis in Human Corneal Epithelial Cells
Pages 827-834
Stapleton, Fiona (et al.)
-
A Functional Unit for Ocular Surface Immune Defense Formed by the Lacrimal Gland, Conjunctiva and Lacrimal Drainage System
Pages 835-844
Knop, Erich (et al.)
-
Role of Tear Anti-Acanthamoeba IgA in Acanthamoeba Keratitis
Pages 845-850
Niederkorn, J. Y. (et al.)
-
Expression of Vascular Endothelial Growth Factor Receptor-3 (Vegfr-3) in the Conjunctiva-A Potential Link Between Lymphangiogenesis and Leukocyte Trafficking on the Ocular Surface
Pages 851-860
Hamrah, Pedram (et al.)
-
Human Lacrimal Drainage-Associated Lymphoid Tissue (LDALT) Belongs to the Common Mucosal Immune System
Pages 861-866
Knop, Erich (et al.)
-
The Crypt System of the Human Conjunctiva
Pages 867-872
Knop, Nadja (et al.)
-
Organized Mucosa-Associated Lymphoid Tissue in Human Nasolacrimal Ducts
Pages 873-876
Paulsen, Friedrich P. (et al.)
-
Contact Lenses and Tear Film Interactions
Pages 879-884
Willcox, Mark (et al.)
-
Effects of O2 Transmissibility on Corneal Epithelium After Daily and Extended Contact Lens Wear in Rabbit and Man
Pages 885-893
Ladage, Patrick M. (et al.)
-
Influence of the Tear Film Composition on Tear Film Structure and Symptomatology of Soft Contact Lens Wearers
Pages 895-899
Guillon, Michel (et al.)
-
Evaluation of the Pre-Lens Tear Film Forming on Three Disposable Contact Lenses
Pages 901-915
Guillon, Jean-Pierre (et al.)
-
An Evaluation of Mucin Balls Associated with High-Dk Silicone-Hydrogel Contact Lens Wear
Pages 917-923
Craig, Jennifer P. (et al.)
-
Cells Collected from the Corneal Surface in Sjögren’s Syndrome, Dry Eye, and Normals
Pages 925-928
Al-Oliky, Salih (et al.)
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The Thickness of the Post-Lens Tear Film Measured by Interferometry
Pages 929-933
Nichols, Jason J. (et al.)
-
Tear Lipid Composition of Hydrogel Contact Lens Wearers
Pages 935-938
Maïssa, Cécile (et al.)
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Conjunctival Characteristics of Contact Lens Wearers and Nonwearers and Their Association with Symptomatology
Pages 939-943
Guillon, Michel (et al.)
-
Dry Eye Symptomatology of Contact Lens Wearers and Nonwearers
Pages 945-949
Guillon, Michel (et al.)
-
Contact Lens-Induced Papillary Conjunctivitis Is Associated With Increased Albumin Deposits On Extended Wear Hydrogel Lenses
Pages 951-955
Tan, Maxine E. (et al.)
-
Surface Protein Profile of Extended-Wear Silicon Hydrogel Lenses
Pages 957-960
Pearce, Damon (et al.)
-
The Detection of Kinin Activity in Contact Lens Wear
Pages 961-966
Aisling, Mann M. (et al.)
-
Immunoblotting and Tear Sampling Techniques for the Study of Contact Lens-Induced Variations in Tear Protein Profiles
Pages 967-971
Peach, Helena C. (et al.)
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Interaction between, the Contact Lens and the Ocular Surface
Pages 973-980
O’Hare, Nicole (et al.)
-
Clinical Benefits and Physical Properties of Addition of Hydroxypropyl Methylcellulose to a Multi-Purpose Contact Lens Care Solution
Pages 981-985
Simmons, Peter A. (et al.)
-
Epidemiology of Dry Eye Syndrome
Pages 989-998
Schaumberg, Debra A. (et al.)
-
Immunogenetics of Autoimmune Exocrinopathy in the Nod Mouse: More Than Meets the Eye
Pages 999-1007
Humphreys-Beher, M. G. (et al.)
-
Results of a Dry Eye Questionnaire from Optometric Practices in North America
Pages 1009-1016
Begley, Carolyn G. (et al.)
-
The Effect of Hormone Replacement Therapy on the Symptoms and Physiologic Parameters of Dry Eye
Pages 1017-1022
Mathers, William D. (et al.)
-
Impaired Neurotransmission in Lacrimal and Salivary Glands of a Murine Model of Sjögren’s Syndrome
Pages 1023-1028
Zoukhri, Driss (et al.)
-
Menopause, Hormone Replacement Therapy and Tear Function
Pages 1029-1033
Evans, Victoria (et al.)
-
IDD3 and IDD5 Alleles From Nod Mice Mediate Sjögren’s Syndrome-Like Autoimmunity
Pages 1035-1039
Cha, S. (et al.)
-
Dry Eye Associated with Chronic Graft-Versus-Host Disease
Pages 1041-1045
Ogawa, Y. (et al.)
-
Contribution of Neurogenic Inflammation to Irritable Eye Syndrome
Pages 1047-1050
Feher, Janos
-
Ocular Drying Associated with Oral Antihistamines (Loratadine) in the Normal Population-an Evaluation of Exaggerated Dose Effect
Pages 1051-1055
Welch, D. (et al.)
-
Evaluation of the Time to “Natural Compensation” in Normal and Dry Eye Subject Populations During Exposure to a Controlled Adverse Environment
Pages 1057-1063
Ousler, G. W., III (et al.)
-
Diagnosis and Treatment of the Dry Eye: A Clinical Perspective
Pages 1067-1078
Nelson, J. Daniel
-
Dry Eye Syndromes: Diagnosis, Clinical Trials and Pharmaceutical Treatment-‘Improving Clinical Trials’
Pages 1079-1086
Abelson, M. B. (et al.)
-
Using Osmolarity to Diagnose Dry Eye: A Compartmental Hypothesis and Review of Our Assumptions
Pages 1087-1095
Anthony, J. Born (et al.)
-
Reliability of Measurements of Tear Physiology
Pages 1097-1105
Tomlinson, Alan (et al.)
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Use of Cevimeline, a Muscarinic Ml and M3 Agonist, in the Treatment of Sjögren’s Syndrome
Pages 1107-1116
Fox, Robert I.
-
Drug Development Issues in Pharmacological Treatments for Dry Eye
Pages 1117-1120
Novack, Gary D.
-
Alternative Reference Values for Tear Film Break up Time in Normal and Dry Eye Populations
Pages 1121-1125
Abelson, Mark B. (et al.)
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Ocular Sensations and Symptoms Associated with Tear Break Up
Pages 1127-1133
Begley, Carolyn G. (et al.)
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Evaluation of the Akorn Dry Eye Test (Dettm) as a Predictor of Contact Lens Comfort
Pages 1135-1140
Higgins, David (et al.)
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Predicting Optical Effects of Tear Film Break Up on Retinal Image Quality Using the Shack-Hartmann Aberrometer and Computational Optical Modeling
Pages 1141-1147
Himebaugh, Nikole L. (et al.)
-
Improvement of Tear Stability Following Warm Compression in Patients with Meibomian Gland Dysfunction
Pages 1149-1152
Goto, Eiki (et al.)
-
An Evaporative Stress Test for Borderline Dry Eye Detection
Pages 1153-1157
Barabino, S. (et al.)
-
Tear Production Measurement, Basal or Reflex Assessment?
Pages 1159-1163
Craig, Jennifer P. (et al.)
-
Innovative Dry Eye Diagnosis System Using Microbalance Technology
Pages 1165-1169
Endo, Koji (et al.)
-
The Repeatability of Diagnostic Tests and Surveys in Dry Eye
Pages 1171-1175
Nichols, Kelly K. (et al.)
-
Association of Clinical Diagnostic Tests and Dry Eye Surveys: The Nei-Vfq-25 and the OSDI
Pages 1177-1181
Nichols, Kelly K. (et al.)
-
Economic and Quality Of Life Impact of Dry Eye Symptoms in Women with Sjögren’s Syndrome
Pages 1183-1188
Sullivan, R. M. (et al.)
-
Patient-Reported Versus Doctor-Diagnosed Dry Eye: The Assessment of Symptoms
Pages 1189-1193
Mitchell, G. Lynn (et al.)
-
Keratoconjunctivitis Sicca Versus Dry Mouth and Autoantibodies in Primary and Secondary Sjögren’s Syndrome
Pages 1195-1199
Kitagawa, Kazuko (et al.)
-
Tear Spreading Rates: Post-Blink
Pages 1201-1204
Owens, Helen (et al.)
-
Near Vision Accommodation in Horizontality with Vdt: Why Low Blinking and Dry Eye?
Pages 1205-1211
Murube, Juan (et al.)
-
Analysis of Tear Protein Patterns for the Diagnosis of Dry Eye
Pages 1213-1216
Grus, Franz H. (et al.)
-
The Significance of Salivary Gland Ultrasonography in the Diagnosis of Dry Eye Syndrome
Pages 1217-1220
Switka-Więcławska, Iwona (et al.)
-
The Effect of Nasal Mucosal Stimulation on Schirmer Tests in Sjögren’s Syndrome and Dry Eye Patients
Pages 1221-1226
Fujisawa, Aya (et al.)
-
A Simple Method of Detecting the Anti-Inflammatory Action of Topical Dry Eye Treatments
Pages 1227-1232
MacKeen, D. L. (et al.)
-
Efficacy of Sodium Hyaluronate Eye Drops of Different Osmolarities in the Symptomatic Treatment of Dry Eye Patients
Pages 1233-1235
Milazzo, Giovanni (et al.)
-
Topical Non-Preserved Diclofenac Therapy for Keratoconjunctivitis Sicca
Pages 1237-1240
Rolando, M. (et al.)
-
The Effect of Botulinum Toxin a Treatment on Tear Function Parameters and on the Ocular Surface
Pages 1241-1246
Horwath-Winter, Jutta (et al.)
-
Efficacy of Autologous Serum Treatment in Patients with Severe Dry Eye
Pages 1247-1250
Takamura, Etsuko (et al.)
-
Ocular Safety of Ins365 Ophthalmic Solution, a P2y2 Agonist, in Patients with Mild to Moderate Dry Eye Disease
Pages 1251-1257
Yerxa, Benjamin R. (et al.)
-
Ocular Surface Reconstruction with Amniotic Membrane Transplantation in Chemical Burn
Pages 1259-1262
Santos, Myrna S. (et al.)
-
Surgical Reconstruction of the Tear Meniscus at the Lower Lid Margin for Treatment of Conjunctivochalasis
Pages 1263-1268
Yokoi, Norihiko (et al.)
-
The Effect of Punctal Occlusion on Tear Lactoferrin in Aqueous Deficient Dry Eye Patients
Pages 1269-1271
Reese, Vernon (et al.)
-
Silicon Punctal Plug Insertion in the Treatment of Severe Dry Eye
Pages 1273-1276
Shinozaki, Kazumi (et al.)
-
Application of Atelocollagen Solution for Lacrimal Duct Occlusion
Pages 1277-1281
Onodera, Jun (et al.)
-
Atelocollagen Punctal Occlusion for the Treatment of the Dry Eye
Pages 1283-1284
Hamano, Takashi
-
Fiberscopic Observation of Canaliculi After Punctal Plug Extrusion
Pages 1285-1288
Shimizu, Kazuhiro (et al.)
-
Neural Stem Cells for Cns Repair: State of the Art and Future Directions
Pages 1291-1296
Park, Kook In (et al.)
-
Particle-Mediated Gene Transfer to Ocular Surface Epithelium
Pages 1297-1308
Kao, Winston W. Y.
-
In Vivo Gene Transfer Into Corneal Epithelial Progenitor Cells By Viral Vectors
Pages 1309-1314
Igarashi, Tsutomu (et al.)
-
Gene Therapy for the Prevention of Corneal Haze after Photorefractive/Phototherapeutic Keratectomy Excimer Laser Surgery
Pages 1315-1321
Behrens, Ashley (et al.)
-
Ex Vivo Preservation and Expansion of Human Limbal Epithelial Stem Cells on Amniotic Membrane for Treating Corneal Diseases with Total Limbal Stem Cell Deficiency
Pages 1323-1334
Tseng, Scheffer C. G. (et al.)
-
Corneal Blindness from End-Stage Sjögren’s Syndrome and Graft-Versus-Host Disease
Pages 1335-1338
Dohlman, Claes H. (et al.)
-
Closing Address: The Academic Perspective
Pages 1341-1342
Ubels, John L.
-
Industry Perspective
Pages 1343-1344
Yerxa, Benjamin R.
-
Addendum
Pages 1345-1348
Sullivan, David A. (et al.)
-
Table of contents (196 chapters)
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Bibliographic Information
- Bibliographic Information
-
- Book Title
- Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3
- Book Subtitle
- Basic Science and Clinical Relevance Part B
- Editors
-
- David A. Sullivan
- Michael E. Stern
- Kazuo Tsubota
- Darlene A. Dartt
- Rose M. Sullivan
- B. Britt Bromberg
- Series Title
- Advances in Experimental Medicine and Biology
- Series Volume
- 506
- Copyright
- 2002
- Publisher
- Springer US
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4615-0717-8
- DOI
- 10.1007/978-1-4615-0717-8
- Hardcover ISBN
- 978-0-306-47282-4
- Softcover ISBN
- 978-1-4613-5208-2
- Series ISSN
- 0065-2598
- Edition Number
- 1
- Number of Pages
- XXX, 1399
- Number of Illustrations
- 176 b/w illustrations, 26 illustrations in colour
- Topics

