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Advances in Behavioral Biology

Biology and Physiology of the Blood-Brain Barrier

Transport, Cellular Interactions, and Brain Pathologies

Editors: Couraud, Pierre-Olivier, Scherman, Daniel (Eds.)

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About this book

The endothelial cells of the cerebral vasculature constitute, together with perivascular elements (astrocytes, pcricytes, basement membrane), the blood-brain barrier (BBB), which strictly limits and specifically controls the exchanges between the blood and the cerebral extracellular spacc.The existence of such a physical, enzymatic, and active barrier isolating the central nervous system has broad physiological, biological, pharmacological, and patho­ logical consequences, most of which are not yet fully elucidated. The Cerebral Vascular Biology conference (CVB '95) was organized and held at the "Carre des Sciences" in Paris on July I 0-12, 1995. Like the CVB '92 conference held in Duluth, Minnesota, three years ago, the objectives were to provide a forum for presentation of the most recent progresses and to stimulate discussions in the ticld of the biology, physiology. and pathology of the blood-brain barrier. The Paris conference gathered more than !50 participants. including investigators in basic neuroscience, physicians. and stu­ dents, who actively contributed to the scientific program by their oral or poster presentations. This volume contains a collection of short articles that summarize most of the new data that were presented at the conference. Six thematic parts focus on physiological transports. drug delivery, multidrug resistance P-glycoprotein, signal transduction at the BBB. interactions between the immune system and the cerebral endothelial cells, and the blood-brain barrier-related pathologies in the central nervous system. In addition, two introductory articles present new insights in the rapidly evolving topics of cerebral angiogenesis and gene transfer to the brain.

Table of contents (63 chapters)

Table of contents (63 chapters)
  • Development of Blood-Brain Barrier Endothelial Cells

    Pages 1-7

    Risau, Werner

  • Prospects for Neuroprotective Gene Therapy for Neurodegenerative Diseases

    Pages 9-10

    Peschanski, Marc

  • Blood-Brain Barrier Taurine Transport and Brain Volume Regulation

    Pages 11-16

    Keep, Richard F. (et al.)

  • Volume Regulation of the in Vitro Blood-Brain Barrier by Osmoreactive Amino Acids during Stress

    Pages 17-19

    Gaillard, P. J. (et al.)

  • A Reduction in the Transfer of Amino Acids Across the Blood-Brain Barrier Might Not be the Sole Mechanism by Which Vasopressin Affects Amino Acid Levels within the Brain

    Pages 21-26

    Reichel, A. (et al.)

Buy this book

eBook 149,79 €
price for Spain (gross)
  • ISBN 978-1-4757-9489-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 258,96 €
price for Spain (gross)
  • ISBN 978-0-306-45362-5
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 187,19 €
price for Spain (gross)
  • ISBN 978-1-4757-9491-5
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Biology and Physiology of the Blood-Brain Barrier
Book Subtitle
Transport, Cellular Interactions, and Brain Pathologies
Editors
  • Pierre-Olivier Couraud
  • Daniel Scherman
Series Title
Advances in Behavioral Biology
Series Volume
46
Copyright
1996
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4757-9489-2
DOI
10.1007/978-1-4757-9489-2
Hardcover ISBN
978-0-306-45362-5
Softcover ISBN
978-1-4757-9491-5
Series ISSN
0099-6246
Edition Number
1
Number of Pages
XVI, 388
Topics

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