Overview
Provides researchers with the modeling and computational studies of physiology
Covers basic methodology, case practices and advanced applications
Sets a paradigm for quantitative physiology by integrating biology, mathematics, physics and informatics
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Table of contents (13 chapters)
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Front Matter
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Applied Methodology
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Front Matter
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Basic Case Studies
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Front Matter
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Complex Applications
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Front Matter
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Keywords
About this book
Stephen Hawking says that the 21st century will be the century of complexity and indeed now systems biology or medicine means dealing with complexity. Both the genome and physiome have emerged in studying complex physiological systems. Computational and mathematical modeling has been regarded as an efficient tool to boost the understanding about living systems in normal or pathophysiological states.
Covering applied methodology, basic case studies and complex applications, this volume provides researchers with an overview of modeling and computational studies of physiology (i.e. quantitative physiology), which is becoming an increasingly important branch of systems biology.
This book aims to build multi-scale models to investigate functions in living systems and explain how biomolecules, cells, organs, organ systems and organisms carry out the chemical or physical functions. Some of the models addressed are related to gene expression, calcium signalling, neural activity, blood dynamics and bone mechanics.
Combining theory and practice, with extensive use of MATLAB, this book is designed to establish a paradigm for quantitative physiology by integrating biology, mathematics, physics and informatics etc.
To benefit from this book, the readers are expected to have a background in general physiology and mathematics
Authors and Affiliations
About the authors
Dr. Shangbin Chen is an Associate Professor from School of Engineering Sciences, Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology. He obtained his Ph.D. from Huazhong University of Science and Technology and completed his postdoc training at University of British Columbia, Canada. His research interests include neuroimaging for brain functions and connectome, computational neuroscience and artificial intelligence. He has published more than 40 research articles in these fields.
Dr. Alexey Zaikin is a Professor and Chair of Systems Medicine and Applied Mathematics, in the Institute for Women’s Health and Department of Mathematics, University College London. He is also Professor of Lobachevsky State University of Nizhny Novgorod and Sechenov University in Russia. His research interests include computational and systems medicine, theoretical biophysics and nonlinear dynamics and stochastic modelling in biology. He has published more than 135 articles in these fields.Bibliographic Information
Book Title: Quantitative Physiology
Book Subtitle: Systems Approach
Authors: Shangbin Chen, Alexey Zaikin
DOI: https://doi.org/10.1007/978-981-33-4033-6
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Huazhong University of Science and Technology Press 2020
Hardcover ISBN: 978-981-33-4032-9Published: 10 February 2021
Softcover ISBN: 978-981-33-4035-0Published: 11 February 2022
eBook ISBN: 978-981-33-4033-6Published: 09 February 2021
Edition Number: 1
Number of Pages: XXI, 237
Number of Illustrations: 149 b/w illustrations, 97 illustrations in colour
Topics: Human Physiology, Systems Biology, Biomedical Engineering/Biotechnology