Overview
- Explains how to design and synthesize bioactive and functional middle-size molecules
- Describes the synthesis of structurally complex middle-size molecules
- Shows how to utilize recently developed methods based on flow chemistry
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Table of contents (19 chapters)
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Front Matter
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Bio-functional Middle Molecules
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Front Matter
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Synthetic Advances in Complex Middle Molecules
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Front Matter
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Synthetic Advances in Aromatic Middle Molecules
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Front Matter
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Synthetic Advances in Flow Chemistry for Middle Molecules
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Front Matter
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Keywords
About this book
This book highlights recently discovered aspects of “middle-size molecules,” focusing on (1) their unique bio-functions on the basis of derivatives and conjugates of natural products, saccharides, peptides, and nucleotides; (2) the synthesis of structurally complex natural products; (3) special synthetic methods for π-conjugated functional molecules; and (4) novel synthetic methods using flow chemistry. Given its scope, the book is of interest to industrial researchers and graduate students in the fields of organic chemistry, medicinal chemistry, and materials science.
Editors and Affiliations
About the editors
Koichi Fukase graduated from the Department of Chemistry, Osaka University, in 1982 and received his Ph.D. from Osaka University (under Prof. Tetsuo Shiba) in 1987. After spending 1 year as a JSPS Postdoctoral Fellow (under Prof. Shiba), he was appointed as Assistant Professor (1988–1996) at the Department of Chemistry, School of Science, Osaka University (under Prof. Shoichi Kusumoto). In 1994, he joined Prof. W. Clark Still’s group at Columbia University as a Ministry of Education Research Fellow. After returning to Osaka in 1995, he was promoted to Lecturer (1996) and Associate Professor (1998) and became Full Professor at the Department of Chemistry, Graduate School of Science, Osaka University, in 2004. He received the Chemical Society of Japan Award for Creative Work in 2011. His research interests include carbohydrate chemistry and glycobiology, synthetic organic chemistry, bio-imaging, and innate immunity.
Takayuki Doi received his Ph.D. from Tokyo Techin 1991 (under Prof. Takashi Takahashi). After a postdoctoral scientist position under Prof. Gilbert Stork at Columbia University, he joined Tokyo Tech as Assistant Professor in 1993 and became Associate Professor in 2001. He was promoted to Full Professor at the Graduate School of Pharmaceutical Sciences, Tohoku University, in 2008 and joined the Graduate School of Life Sciences in 2018. He received the Progress Award in Synthetic Organic Chemistry, Japan in 2000, and the Pharmaceutical Society of Japan Award for Divisional Scientific Promotions in 2013.
Bibliographic Information
Book Title: Middle Molecular Strategy
Book Subtitle: Flow Synthesis to Functional Molecules
Editors: Koichi Fukase, Takayuki Doi
DOI: https://doi.org/10.1007/978-981-16-2458-2
Publisher: Springer Singapore
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2021
Hardcover ISBN: 978-981-16-2457-5Published: 14 July 2021
Softcover ISBN: 978-981-16-2460-5Published: 15 July 2022
eBook ISBN: 978-981-16-2458-2Published: 13 July 2021
Edition Number: 1
Number of Pages: X, 357
Number of Illustrations: 180 b/w illustrations, 101 illustrations in colour
Topics: Bioorganic Chemistry, Medicinal Chemistry, Pharmaceutical Sciences/Technology, Pharmacy