Microbial Communication

Mathematical Modeling, Synthetic Biology and the Role of Noise

Authors: Majumdar, Sarangam, Roy, Sisir

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  • Elaborates on all the different kinds of microbial communication systems
  • Describes the role of noise in the context of microbial communication
  • Provides insights into the mathematical models, experimental observations, synthetic biology and the relevance of quantum theory in understanding microbial communication
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About this book

This book introduces the concept of bacterial communication systems from a mathematical modeling point of view. It sheds light on the research undertaken in the last three decades, and the mathematical models that have been proposed to understand the underlying mechanism of such systems. These communication systems are related to quorum sensing mechanisms and quorum sensing regulated processes such as biofilm formation, gene expression, bioluminescence, swarming and virulence. 

The book further describes the phenomenon of noise, and discusses how noise plays a crucial role in gene expression and the quorum sensing circuit operationusing a set of tools like frequency domain analysis, power spectral density, stochastic simulation and the whitening effect. It also explores various aspects of synthetic biology (related to bacterial communication), such as genetic toggle switch, bistable gene regulatory networks, transcriptional repressor systems, pattern formation, synthetic cooperation, predator-prey synthetic systems, dynamical quorum sensing, synchronized quorum of genetic clocks, role of noise in synthetic biology, the Turing test and stochastic Turing test.


About the authors

Sarangam Majumdar is a mathematician. He holds a Bachelor of Science and Master of Science in Mathematics from the University of Calcutta (2010) and National Institute of Technology, Rourkela (2012), respectively. He has worked with Prof. Sisir Roy, Indian Statistical Institute, Kolkata; Prof. Rodolfo Llinas, New York University School of Medicine, USA; Prof. Dr. Suman Datta, University of Calcutta; Prof. S. Chakraverty, National Institute of Technology, Rourkela; Dr. Sukla Pal, University of Otago,NewZeland; Prof. Rodolfo Repetto, Dipartimento di Ingegneriadelle Costruzioni, dell'Ambiente e del Territorio, Università degl iStudi di Genova, Italy; Prof. Nicola Guglielmi, Università degli Studi di L' Aquila and many more. His research interests include mathematical biology, system biology, mathematical modeling, numerical analysis, scientific computing, nonlinear dynamics and chaos, and over the past eight yearshe has focused on bacterial communication systems (quorum sensing, electrical communication). He has published several papers in various peer-reviewed, international journals and book chapters (in Springer). He is also a reviewer for a number of international journals.

Prof. Sisir Roy is a theoretical physicist currently working as a Visiting Professor and Senior Homi Bhabha Fellow, National Institute of Advanced Studies, IISc Campus, Bangalore. Previously he worked as a Professor at the Physics and Applied Mathematics Unit, Indian Statistical Institute, Kolkata from 1980 to 2014, and as a Visiting Scientist at the Institute Henri Poincare, Paris, France, from 1986 to 87. He has also worked as a Distinguished Visiting Professor at numerous US and European Universities. He has collaborated with Prof. J.P. Vigier, France; Prof. Bo Lehnert, Alfven Laboratory, Sweden; Prof. Menas Kafatos, George Mason University; Prof. Ralph Abraham, University of California; and Prof. Rodolfo Llinas, New York University School of Medicine, NY,USA. His main interests includethe foundations of quantum theory, theoretical astrophysics, quantum biology, brain function modeling and higher-order cognitive activities. He has published more than two hundred papers in various peer-reviewed, international journals, twelve monographs and edited volumes published by Kluwer Academic Publishers, World Scientific, Singapore, Springer and others.  He is currently a member of the editorial boards of various international journals. His recent books include: Sisir Roy (2016) Decision making and modeling in cognitive science, Springer


Table of contents (15 chapters)

Table of contents (15 chapters)

Buy this book

eBook £103.50
price for United Kingdom (gross)
  • ISBN 978-981-15-7417-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover £129.99
price for United Kingdom (gross)
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Bibliographic Information

Bibliographic Information
Book Title
Microbial Communication
Book Subtitle
Mathematical Modeling, Synthetic Biology and the Role of Noise
Authors
Copyright
2020
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-15-7417-7
DOI
10.1007/978-981-15-7417-7
Hardcover ISBN
978-981-15-7416-0
Edition Number
1
Number of Pages
XVII, 175
Number of Illustrations
17 b/w illustrations, 18 illustrations in colour
Topics