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Advances in Experimental Medicine and Biology
cover

Coronary Artery Disease: Therapeutics and Drug Discovery

Editors: Wang, Miao (Ed.)

  • Providing a cutting-edge understanding of the mechanisms of coronary artery disease (CAD)
  • Highlighting the drug pharmacology and therapeutic challenges to treat CAD
  • Emphasizing the development for CAD, principles of therapeutics and on-going new drug research
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Buy this book

eBook £95.50
price for United Kingdom (gross)
  • The eBook version of this title will be available soon
  • Due: April 29, 2020
  • ISBN 978-981-15-2517-9
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
Hardcover £119.99
price for United Kingdom (gross)
  • Due: April 29, 2020
  • ISBN 978-981-15-2516-2
  • Free shipping for individuals worldwide
About this book

This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease.

The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges.

The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued.

Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.

About the authors

Dr. Miao Wang is a Professor and Head of the Laboratory of Vascular Biology and Pharmacology, State Key Laboratory of Cardiovascular Disease (SKLCD), National Center for Cardiovascular Disease, Peking Union Medical College & Chinese Academy of Medical Sciences. Before joining the SKLCD, Dr. Wang worked as the principal scientist at the Cardiovascular and Metabolic Disease Research Unit, Pfizer Inc. A lifetime member of the Sino-American Pharmaceutical Professionals Association, his research focuses on the mechanisms of coronary artery disease, particularly those related to inflammation and thrombosis, and on the translation of novel mechanistic insights into therapeutic innovations. He has published more than 30 research articles in the field’s leading journals.

Buy this book

eBook £95.50
price for United Kingdom (gross)
  • The eBook version of this title will be available soon
  • Due: April 29, 2020
  • ISBN 978-981-15-2517-9
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
Hardcover £119.99
price for United Kingdom (gross)
  • Due: April 29, 2020
  • ISBN 978-981-15-2516-2
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Coronary Artery Disease: Therapeutics and Drug Discovery
Editors
  • Miao Wang
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1177
Copyright
2020
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-15-2517-9
DOI
10.1007/978-981-15-2517-9
Hardcover ISBN
978-981-15-2516-2
Series ISSN
0065-2598
Edition Number
1
Number of Pages
IX, 339
Number of Illustrations
3 b/w illustrations, 4 illustrations in colour
Topics