Overview
- Compiles the recent advancements in Synthetic Biology and its biotechnological, industrial and biomedical applications
- Reviews the state-of-the-art tools and technologies for DNA synthesis, DNA sequencing, genome designing, and assembly
- Describes the cell-free protein synthesis systems, non-coding DNA, automaton computing, expansion of genetic code, and microfluidics for lab-on-chip and cell dynamics analysis
- Outlines the function of small non-coding RNA for gene regulation, biosensor, and therapeutic applications
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Table of contents (20 chapters)
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Front Matter
Keywords
About this book
This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more.
The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.
Editors and Affiliations
About the editor
Dr. Vijai Singh is an Associate Professor at the Department of Biosciences, Indrashil University, Mehsana, Gujarat, India. He previously served as a Postdoctoral Fellow at the Institute of Systems and Synthetic Biology, France and at the School of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology, South Korea. Dr. Singh has also served as an Assistant Professor at Department of Biotechnology, Invertis University, India and the Department of Biological Sciences and Biotechnology, Institute of Advanced Research, India. He received his Ph.D. in Biotechnology from Dr. A.P.J. Abdul Kalam Technical University/National Bureau of Fish Genetic Resources, Lucknow, India.
Dr. Singh has designed and characterized a number of synthetic oscillators, gene regulatory networks, and biosynthetic pathways in Escherichia coli. Currently, his laboratory is focusing on the construction of a novel biosynthetic pathway for the production of pigments and chemicals. Additionally, his laboratory works on development of CRISPR-based platform for the diagnosis and eradication of multidrug resistant pathogens. Dr. Singh has published 72 articles, 23 book chapters, and two books. He currently serves as a member of the editorial board and reviewer for a number of peer-reviewed journals.
Bibliographic Information
Book Title: Advances in Synthetic Biology
Editors: Vijai Singh
DOI: https://doi.org/10.1007/978-981-15-0081-7
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2020
Hardcover ISBN: 978-981-15-0080-0Published: 14 April 2020
Softcover ISBN: 978-981-15-0083-1Published: 26 August 2021
eBook ISBN: 978-981-15-0081-7Published: 13 April 2020
Edition Number: 1
Number of Pages: XIII, 349
Number of Illustrations: 1 b/w illustrations
Topics: Systems Biology, Genetic Engineering, Gene Expression, Gene Function, Circuits and Systems