Overview
- Describes two major in vivo inhalation-toxicity screening methods: the short-term inhalation study (STIS) and intratracheal administration
- Collects up-to-date information on test procedures and interpretation of the results, useful applications and related technologies for each inhalation toxicity screening method
- Provides a pragmatic reference resource for those responsible for safety assessments of nanomaterials in R&D and business, as well as researchers
Part of the book series: Current Topics in Environmental Health and Preventive Medicine (CTEHPM)
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Table of contents (11 chapters)
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Front Matter
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Short-Term Inhalation Study
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Front Matter
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Intratracheal Administration Study
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Front Matter
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Keywords
About this book
This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials.
With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.
Reviews
Editors and Affiliations
About the editors
Toru Takebayashi
Keio University
Graduate School of Health Management
Fujisawa, Kanagawa, Japan
Robert Landsiedel
BASF SE
Experimental Toxicology and Ecology
Ludwigshafen am Rhein, Germany
Masashi Gamo
National Institute of Advanced Industrial Science and Technology (AIST)
Tsukuba, Ibaraki, Japan
Bibliographic Information
Book Title: In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials
Editors: Toru Takebayashi, Robert Landsiedel, Masashi Gamo
Series Title: Current Topics in Environmental Health and Preventive Medicine
DOI: https://doi.org/10.1007/978-981-13-8433-2
Publisher: Springer Singapore
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2019
Hardcover ISBN: 978-981-13-8432-5Published: 03 September 2019
Softcover ISBN: 978-981-13-8435-6Published: 03 September 2020
eBook ISBN: 978-981-13-8433-2Published: 20 August 2019
Series ISSN: 2364-8333
Series E-ISSN: 2364-8341
Edition Number: 1
Number of Pages: VI, 223
Number of Illustrations: 8 b/w illustrations, 62 illustrations in colour
Topics: Health Promotion and Disease Prevention, Health Administration, Pharmacology/Toxicology