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Current Topics in Environmental Health and Preventive Medicine

In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials

Editors: Takebayashi, Toru, Landsiedel, Robert, Gamo, Masashi (Eds.)

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  • Describes two major in vivo inhalation-toxicity screening methods: the short-term inhalation study (STIS) and intratracheal administration
  • Collects up-to-date information on test procedures and interpretation of the results, useful applications and related technologies for each inhalation toxicity screening method
  • Provides a pragmatic reference resource for those responsible for safety assessments of nanomaterials in R&D and business, as well as researchers
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eBook £71.50
price for United Kingdom (gross)
  • ISBN 978-981-13-8433-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £119.99
price for United Kingdom (gross)
  • Due: September 20, 2019
  • ISBN 978-981-13-8432-5
  • Free shipping for individuals worldwide
About this book

This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials.

With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.


About the authors

Toru Takebayashi
Keio University
Graduate School of Health Management
Fujisawa, Kanagawa, Japan

Robert Landsiedel
BASF SE
Experimental Toxicology and Ecology
Ludwigshafen am Rhein, Germany


Masashi Gamo
National Institute of Advanced Industrial Science and Technology (AIST)
Tsukuba, Ibaraki, Japan


Table of contents (11 chapters)

Table of contents (11 chapters)
  • The Role of In Vivo Screening Studies in Assessing Manufactured Nanomaterials

    Pages 1-21

    Landsiedel, Robert (et al.)

  • The Short-Term Inhalation Study (STIS) as a Range Finder and Screening Tool in a Tiered Grouping Strategy

    Pages 25-65

    Wiench, Karin (et al.)

  • Use of Short-Term Inhalation Study to Obtain Initial Hazard Data and Prepare for Subacute and Subchronic Inhalation Studies, and Toxicokinetic Studies

    Pages 67-77

    Jeon, Ki Soo (et al.)

  • Subchronic Inhalation Toxicity Study with a Vapor-Grown Carbon Nanofiber in Male and Female Rats (OECD 413): Does Nanofiber Exposure Have Adverse Impacts on the Cardiovascular System?

    Pages 79-91

    Warheit, David B.

  • Comparison of Responses in Rat Lung Following Inhalation and Intratracheal Administration of Nanoparticles

    Pages 95-105

    Yoshiura, Yukiko (et al.)

Buy this book

eBook £71.50
price for United Kingdom (gross)
  • ISBN 978-981-13-8433-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £119.99
price for United Kingdom (gross)
  • Due: September 20, 2019
  • ISBN 978-981-13-8432-5
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials
Editors
  • Toru Takebayashi
  • Robert Landsiedel
  • Masashi Gamo
Series Title
Current Topics in Environmental Health and Preventive Medicine
Copyright
2019
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-13-8433-2
DOI
10.1007/978-981-13-8433-2
Hardcover ISBN
978-981-13-8432-5
Series ISSN
2364-8333
Edition Number
1
Number of Pages
VI, 223
Number of Illustrations
8 b/w illustrations, 62 illustrations in colour
Topics